Abstract
Pathologic myopia is one of the major causes of visual impairment worldwide, the prevalence of which has been reported to be about 1% of the population [1–5]. The visual loss is mainly caused by pathological structural changes, such as lacquer crack formation, posterior staphyloma, thinning of the retina, choroid and sclera, retinal schisis, deformation of the optic disc area, and choroidal neovascularization (CNV) [6–9]. Optical coherence tomography (OCT) is very efficient in non-invasive detection of these myopic lesions. The newer generation of OCT, swept source OCT (SS-OCT), has an increased depth of imaging and also a higher speed of scanning, which has made it one of the most useful imaging devices for characterizing pathologic myopia [10–12].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Green JS, Bear JC, Johnson GJ. The burden of genetically determined eye disease. Br J Ophthalmol. 1986;70:696–9.
Krumpaszky HG, Lüdtke R, Mickler A, Klauss V, Selbmann HK. Blindness incidence in Germany. A population-based study from Wurttemberg-Hohenzollern. Ophthalmologica. 1999;213:176–82.
Munier A, Gunning T, Kenny D, O’Keefe M. Causes of blindness in the adult population of the Republic of Ireland. Br J Ophthalmol. 1998;82:630–3.
Cotter SA, Varma R, Ying-Lai M, Azen SP, Klein R. Causes of low vision and blindness in adult Latinos: the Los Angeles Latino Eye Study. Ophthalmology. 2006;113:1574–82.
Vongphanit J, Mitchell P, Wang JJ. Prevalence and progression of myopic retinopathy in an older population. Ophthalmology. 2002;109:704–11.
Takano M, Kishi S. Foveal retinoschisis and retinal detachment in severely myopic eyes with posterior staphyloma. Am J Ophthalmol. 1999;128:472–6.
Ohno-Matsui K, Shimada N, Yasuzumi K, Hayashi K, Yoshida T, Kojima A, et al. Long-term development of significant visual field defects in highly myopic eyes. Am J Ophthalmol. 2011;152:256–65.
Hayashi K, Ohno-Matsui K, Shimada N, Moriyama M, Kojima A, Hayashi W, et al. Long-term pattern of progression of myopic maculopathy: a natural history study. Ophthalmology. 2010;117:1595–611.
Curtin BJ. Basic science and clinical management. In: Curtin BJ, editor. The myopias. New York: Harper and Row; 1985.
Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009;148:445–50.
Ohno-Matsui K, Akiba M, Moriyama M, Ishibashi T, Tokoro T, Spaide RF. Imaging the retrobulbar subarachnoid space around the optic nerve by swept source optical coherence tomography in eyes with pathologic myopia. Invest Ophthalmol Vis Sci. 2011;52:9644–50.
Zhou M, Wang W, Ding X, Huang W, Chen S, Laties AM, et al. Choroidal thickness in fellow eyes of patients with acute primary angle-closure measured by enhanced depth imaging spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2013;54:1971–8.
Spaide RF. Staphyloma: part 1. In: Spaide RF, Ohno-Matsui K, Yannuzzi LA, editors. Pathologic myopia. New York: Springer; 2013.
Curtin BJ. The posterior staphyloma of pathologic myopia. Trans Am Ophthalmol Soc. 1977;75:67–86.
Ohno-Matsui K. Proposed classification of posterior staphylomas based on analyses of eye shape by three-dimentional magnetic resonance imaging and wide-field fundus imaging. Ophthalmology. 2014;121:1798–809.
Sayanagi K, Morimoto Y, Ikuno Y, Tano Y. Spectral-domain optical coherence tomographic findings in myopic foveoschisis. Retina. 2010;30(4):623–8.
Benhamou N, Massin P, Haouchine B, Erginay A, Gaudric A. Macular retinoschisis in highly myopic eyes. Am J Ophthalmol. 2002;133(6):794–800.
Panozzo G, Mercanti A. Optical coherence tomography findings in myopic traction maculopathy. Arch Ophthalmol. 2004;122(10):1455–60.
Baba T, Ohno-Matsui K, Futagami S, Yoshida T, Yasuzumi K, Kojima A, et al. Prevalence and characteristics of foveal retinal detachment without macular hole in high myopia. Am J Ophthalmol. 2003;135(3):338–42.
Mitry D, Zambarakji H. Recent trends in the management of maculopathy secondary to pathological myopia. Graefes Arch Clin Exp Ophthalmol. 2012;250:3–13.
Gonvers M, Machemer R. A new approach to treating retinal detachment with macular hole. Am J Ophthalmol. 1982;94:468–72.
Ortisi E, Avitabile T, Bonfiglio V. Surgical management of retinal detachment because of macular hole in highly myopic eyes. Retina. 2012;32:1074–8.
Kuriyama S, Hayashi H, Jingami Y, Kuramoto N, Akita J, Matsumoto M. Efficacy of inverted internal limiting membrane flap technique for the treatment of macular hole in high myopia. Am J Ophthalmol. 2013;156:125–31.
Kadonosono K, Yazawa F, Itoh N, Uchio E, Nakamura S, Akura J, et al. Treatment of retinal detachment resulting from myopic macular hole with internal limiting membrane removal. Am J Ophthalmol. 2001;131:203–7.
Ichibe M, Yoshizaka T, Murakami K, Ohta M, Oya Y, Yamamoto S, et al. Surgical management of retinal detachment associated with myopic macular hole: anatomic and functional status of the macula. Am J Ophthalmol. 2003;136:277–84.
Curtin BJ, Karlin DB. Axial length measurements and fundus changes of the myopic eye. Am J Ophthalmol. 1971;71:42–53.
Yoshida T, Ohno-Matsui K, Yasuzumi K, Kojima A, Shimada N, Futagami S, et al. Myopic choroidal neovascularization: a 10-year follow-up. Ophthalmology. 2003;110:1297–305.
Wang NK, Lai CC, Chou CL, Chen YP, Chuang LH, Chao AN, et al. Choroidal thickness and biometric markers for the screening of lacquer cracks in patients with high myopia. PLoS One. 2013;8(1):e53660.
El Matri L, Bouladi M, Chebil A, Kort F, Largueche L, Mghaieth F. Macular choroidal thickness assessment with SD-OCT in high myopia with or without choroidal neovascularization. J Fr Ophtalmol. 2013;36:687–92.
Lai TY, Luk FO, Lee GK, Lam DS. Long-term outcome of intravitreal anti-vascular endothelial growth factor therapy with bevacizumab or ranibizumab as primary treatment for subfoveal myopic choroidal neovascularization. Eye (Lond). 2012;26:1004–11.
Tufail A, Patel PJ, Sivaprasad S, Amoaku W, Browning AC, Cole M, et al. Ranibizumab for the treatment of choroidal neovascularisation secondary to pathological myopia: interim analysis of the REPAIR study. Eye (Lond). 2013;27:709–15.
Wolf S, Balciuniene VJ, Laganovska G, Menchini U. Ohno-Matsui K5, Sharma T, et al. RADIANCE: A randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia. Ophthalmology. 2014;121(3):682–92.
Freund KB, Ciardella AP, Yannuzzi LA, Pece A, Goldbaum M, Kokame GT, et al. Peripapillary detachment in pathologic myopia. Arch Ophthalmol. 2003;121(2):197–204.
Toranzo J, Cohen SY, Erginay A, Gaudric A. Peripapillary intrachoroidal cavitation in myopia. Am J Ophthalmol. 2005;140(4):731–2.
Gaucher D, Erginay A, Lecleire-Collet A, Haouchine B, Puech M, Cohen SY, et al. Dome-shaped macula in eyes with myopic posterior staphyloma. Am J Ophthalmol. 2008;145(5):909–14.
Imamura Y, Iida T, Maruko I, Zweifel SA, Spaide RF. Enhanced depth imaging optical coherence tomography of the sclera in dome-shaped macula. Am J Ophthalmol. 2011;151(2):297–302.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Maeda, A., Hirashima, T., Oh, H. (2017). Pathological Myopia. In: Michalewska, Z., Nawrocki, J. (eds) Atlas of Swept Source Optical Coherence Tomography . Springer, Cham. https://doi.org/10.1007/978-3-319-49840-9_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-49840-9_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-49839-3
Online ISBN: 978-3-319-49840-9
eBook Packages: MedicineMedicine (R0)