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Seizures in Critical Care pp 19–29Cite as

Impact of Seizures on Outcome

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Part of the book series: Current Clinical Neurology ((CCNEU))

Abstract

Clinical seizures occur frequently in the critically ill patient. In addition, the increasing application and recent widespread use of continuous electroencephalogram monitoring have revealed that electrographic seizures are even more frequent than clinical seizures in the critically ill patient. There are limited data on how electrographic seizures affect outcome and whether and how aggressively to treat electrographic seizures in the critically ill patient. This review aims to address this gap in knowledge by summarizing the impact of electrographic seizures on outcome and providing a general guide to treat electrographic seizures in the critically ill patient. Current literature suggests that electrographic seizures likely worsen outcome independent of the underlying etiology. This association is stronger in subarachnoid hemorrhage and in traumatic brain injury and warrants a proactive treatment. In contrast, the presence of electrographic seizures in stroke or tumors is unlikely to modify outcomes.

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Authors and Affiliations

  1. Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA, 02115, USA

    Iván Sánchez Fernández & Tobias Loddenkemper

  2. Department of Child Neurology, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain

    Iván Sánchez Fernández

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  1. Iván Sánchez Fernández
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  2. Tobias Loddenkemper
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Correspondence to Tobias Loddenkemper .

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Editors and Affiliations

  1. Departments of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA

    Panayiotis N. Varelas

  2. Neurocritical Care, Columbia University College of Physicians & Surgeons, New York, New York, USA

    Jan Claassen

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Sánchez Fernández, I., Loddenkemper, T. (2017). Impact of Seizures on Outcome. In: Varelas, P., Claassen, J. (eds) Seizures in Critical Care. Current Clinical Neurology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-49557-6_2

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