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Outcome of Critically Ill Allogeneic Hematopoietic Stem-Cell Transplantation Recipients

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Mechanical Ventilation in Critically Ill Cancer Patients

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Abstract

Allogeneic hematopoietic stem cell transplant (HSCT) has become a standard treatment modality for hematological malignancies. Chemotherapy toxicity, infection, and syndromes associated with the graft and host interaction frequently jeopardize the health of these patients so significantly that they require admission to the intensive care unit (ICU). Despite improvements in the delivery of critical care services to allogeneic HSCT patients, ICU mortality rates remain high. Certain complications, particularly those involving the respiratory system, are strongly influenced by the length of time that has elapsed since transplant. Most allogeneic HSCT patients should receive critical care services, contrary to a widely held belief that excessive ICU-related morbidity and mortality preclude any meaningful chance of recovery.

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Author information

Authors and Affiliations

  1. Section of Pulmonary and Critical Care Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, USA

    Darius Seidler M.D. & Alex H. Gifford M.D.

Authors
  1. Darius Seidler M.D.
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  2. Alex H. Gifford M.D.
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Corresponding author

Correspondence to Alex H. Gifford M.D. .

Editor information

Editors and Affiliations

  1. Intensive Care and Non Invasive Ventilatory Unit, Hospital Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

  2. Division of Anesthesiology and Critical Care, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

    S. Egbert Pravinkumar

  3. Wayne State University School of Medicine, Detroit, Michigan, USA

    AYMAN O. SOUBANI

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Seidler, D., Gifford, A.H. (2018). Outcome of Critically Ill Allogeneic Hematopoietic Stem-Cell Transplantation Recipients. In: Esquinas, A., Pravinkumar, S., SOUBANI, A. (eds) Mechanical Ventilation in Critically Ill Cancer Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-49256-8_31

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  • DOI: https://doi.org/10.1007/978-3-319-49256-8_31

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-49256-8

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