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Effect of Aging on Cardiac Function Plus Monitoring and Support

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References

  1. Crispell KA. Common cardiovascular issues encountered in geriatric critical care. Crit Care Clin. 2003;19(4):677–91.

    Article  PubMed  Google Scholar 

  2. Thomas S, Rich M. Epidemiology, pathophysiology, and prognosis of heart failure in the elderly. Heart Fail Clin. 2007;3(4):381–7.

    Article  PubMed  Google Scholar 

  3. McGwin Jr G, MacLennan PA, Fife JB, Davis GG, Rue III LW. Preexisting conditions and mortality in older trauma patients. J Trauma. 2004;56(6):1291–6.

    Article  PubMed  Google Scholar 

  4. Sandstede J, Lipke C, Beer M, et al. Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol. 2000;10(3):438–42.

    Article  CAS  PubMed  Google Scholar 

  5. Innelli P, Esposito R, Olibet M, Nistri S, Galderisi M. The impact of aging on right ventricular longitudinal function in healthy subjects: a pulsed tissue Doppler study. Eur J Echocardiogr. 2009;10(4):491–8.

    Article  PubMed  Google Scholar 

  6. Lindqvist P, Waldenstrom A, Henein M, Morner S, Kazzam E. Regional and global right ventricular function in healthy individuals aged 20–90 years: a pulsed Doppler tissue imaging study: Umea General Population Heart Study. Echocardiography. 2005;22(4):305–14.

    Article  PubMed  Google Scholar 

  7. Lakatta EG. Do hypertension and aging have a similar effect on the myocardium? Circulation. 1987;75(1 Pt 2):I69–77.

    CAS  PubMed  Google Scholar 

  8. Strait JB, Lakatta EG. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail Clin. 2012;8(1):143–64.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Ugander M, Oki AJ, Hsu L-Y, et al. Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology. Eur Heart J. 2012;33(10):1268–78.

    Google Scholar 

  10. Liu C-Y, Liu YC, Wu C, et al. Evaluation of age-related interstitial myocardial fibrosis with cardiac magnetic resonance contrast-enhanced T1 Mapping in the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2013;62(14):1280–7. doi:10.1016/j.jacc.2013.05.078.

  11. Chen W, Frangogiannis NG. The role of inflammatory and fibrogenic pathways in heart failure associated with aging. Heart Fail Rev. 2010;15(5):415–22.

    Google Scholar 

  12. Duggan J. In: Horan MA, Little RA, editors. Injury in the aging. Cambridge: Cambridge University Press; 1998.

    Google Scholar 

  13. O’Rourke M. Mechanical principles in arterial disease. Hypertension. 1995;26(1):2–9.

    Google Scholar 

  14. Greenwald SE. Ageing of the conduit arteries. J Pathol. 2007;211(2):157–72.

    Google Scholar 

  15. Izzo Jr JL. Arterial stiffness and the systolic hypertension syndrome. Curr Opin Cardiol. 2004;19(4):341–52.

    Google Scholar 

  16. Nichols WW, Edwards DG. Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy. J Cardiovasc Pharmacol Ther. 2001;6(1):5–21.

    Google Scholar 

  17. Duggan J, Kilfeather S, O’Brien E, O’Malley K, Nussberger J. Effects of aging and hypertension on plasma angiotensin II and platelet angiotensin II receptor density. Am J Hypertens. 1992;5(10):687–93.

    Google Scholar 

  18. Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res. 1991;68(6):1560–8.

    Google Scholar 

  19. Cheng S, Fernandes VR, Bluemke DA, McClelland RL, Kronmal RA, Lima JA. Age-related left ventricular remodeling and associated risk for cardiovascular outcomes: the Multi-Ethnic Study of Atherosclerosis. Circ Cardiovasc Imaging. 2009;2(3):191–8.

    Google Scholar 

  20. Christou DD, Seals DR. Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate. J Appl Physiol. 2008;105(1):24–9.

    Google Scholar 

  21. Kistler PM, Sanders P, Fynn SP, et al. Electrophysiologic and electroanatomic changes in the human atrium associated with age. J Am Coll Cardiol. 2004;44(1):109–16.

    Google Scholar 

  22. Jones SA, Boyett MR, Lancaster MK. Declining into failure: the age-dependent loss of the L-type calcium channel within the sinoatrial node. Circulation. 2007;115(10):1183–90.

    Google Scholar 

  23. Gribben B, Pickering TG, Sleight P, Peto R. Effect of age and high blood pressure on baroreflex sensitivity in man. Circ Res. 1971;29:424–31.

    Google Scholar 

  24. Shannon RP, Wei JY, Rosa RM, Epstein FH, Rowe JW. The effect of age and sodium depletion on cardiovascular response to orthostasis. Hypertension. 1986;8(5):438–43.

    Google Scholar 

  25. Shimada K, Kitazumi T, Sadakane N, Ogura H, Ozawa T. Age-related changes of baroreflex function, plasma norepinephrine, and blood pressure. Hypertension. 1985;7(1):113–7.

    Google Scholar 

  26. Duggan J, Nussberger J, Kilfeather S, O’Malley K. Aging and human hormonal and pressor responsiveness to angiotensin II infusion with simultaneous measurement of exogenous and endogenous angiotensin II. Am J Hypertens. 1993;6(8):641–7.

    Google Scholar 

  27. Rodeheffer RJ, Gerstenblith G, Becker LC, Fleg JL, Weisfeldt ML, Lakatta EG. Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate. Circulation. 1984;69(2):203–13.

    Google Scholar 

  28. Port S, Cobb FR, Coleman RE, Jones RH. Effect of age on the response of the left ventricular ejection fraction to exercise. N Engl J Med. 1980;303(20):1133–7.

    Google Scholar 

  29. Ford GA, James OF. Effect of ‘autonomic blockade’ on cardiac beta-adrenergic chronotropic responsiveness in healthy young, healthy elderly and endurance-trained elderly subjects. Clin Sci (Lond). 1994;87(3):297–302.

    Google Scholar 

  30. Innelli P, Sanchez R, Marra F, Esposito R, Galderisi M. The impact of aging on left ventricular longitudinal function in healthy subjects: a pulsed tissue Doppler study. Eur J Echocardiogr. 2008;9(2):241–9.

    PubMed  Google Scholar 

  31. Belzberg H, Wo CC, Demetriades D, Shoemaker WC. Effects of age and obesity on hemodynamics, tissue oxygenation, and outcome after trauma. J Trauma. 2007;62(5):1192–200.

    Article  PubMed  Google Scholar 

  32. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part II: the aging heart in health: links to heart disease. Circulation. 2003;107(2):346–54.

    Article  PubMed  Google Scholar 

  33. Hadi HA, Alsheikh-Ali AA, Mahmeed WA, Suwaidi JM. Inflammatory cytokines and atrial fibrillation: current and prospective views. J Inflamm Res. 2010;3:75–97.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  34. Frink M, van Griensven M, Kobbe P, et al. IL-6 predicts organ dysfunction and mortality in patients with multiple injuries. Scand J Trauma Resusc Emerg Med. 2009;17:49.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Solti F, Vecsey T, Kekesi V. Effect of atrial dilatation on the tendency of atrial arrhythmias. Acta Physiol Hung. 1989;74(1):49–55.

    CAS  PubMed  Google Scholar 

  36. Amar D, Zhang H, Leung DH, Roistacher N, Kadish AH. Older age is the strongest predictor of postoperative atrial fibrillation. Anesthesiology. 2002;96(2):352–6.

    Article  PubMed  Google Scholar 

  37. The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med. 2002;347:1825–33.

    Article  Google Scholar 

  38. Hadjizacharia P, O'Keeffe T, Brown CVR, Inabi K, Salim A, Chan LS, Demetriades D, Rhee P. Incidence, risk factors, and outcomes for atrial arrhythmias in trauma patients. Am Surg. 2011;77(5):634–9.

    PubMed  Google Scholar 

  39. Moosikasuwan JB, Thomas JM, Buchman TG. Myocardial infarction as a complication of injury. J Am Coll Surg. 2000;190(6):665–70.

    Article  CAS  PubMed  Google Scholar 

  40. Perdue PW, Watts DD, Kaufmann CR, Trask AL. Differences in mortality between elderly and younger adult trauma patients: geriatric status increases risk of delayed death. J Trauma. 1998;45(4):805–10.

    Article  CAS  PubMed  Google Scholar 

  41. Alcalai R, Planer D, Culhaoglu A, Osman A, Pollak A, Lotan C. Acute coronary syndrome vs nonspecific troponin elevation: clinical predictors and survival analysis. Arch Intern Med. 2007;167(3):276–81.

    Article  PubMed  Google Scholar 

  42. Borlaug BA, Olson TP, Lam CS, et al. Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2010;56(11):845–54.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to R. Shayn Martin MD .

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Avery, M.D., Martin, R.S., Chang, M.C. (2017). Effect of Aging on Cardiac Function Plus Monitoring and Support. In: Luchette, F., Yelon, J. (eds) Geriatric Trauma and Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-319-48687-1_2

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  • DOI: https://doi.org/10.1007/978-3-319-48687-1_2

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