Abstract
In recent years, there has been an increased focus on delivering appropriate, efficient, and effective medical care. As a result of this, a number of tools and techniques have been developed and increasingly used to assist in this process. One such entity is that of care bundles or, more simply, bundles. These are a set of evidence-based interventions that, when implemented together, tend to result in significantly better outcomes than when implemented individually [1]. Bundles usually consistent of three to five elements and are targeted for a defined patient population or care setting. Their effectiveness is centered on bringing together independent practices and tying them into a package that needs to be completed for each encounter with these patients or care settings [2].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Resar R, Griffin FA, Haraden C, Nolan TW. Using care bundles to improve health care quality. IHI innovation series white paper. Cambridge, MA: Institute for Healthcare Improvement; 2012. www.IHI.org. Accessed 2 Jun 2014
Haraden C. What is a bundle. Cambridge, MA: The Institute of Healthcare Improvement; 2014. www.IHI.org. Accessed 1 Jul 2014
Horner DL, Bellamy MC. Care bundles in intensive care. Contin Educ Anaesth Crit Care Pain. 2012;12:199–202.
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345:1368–77.
Masterton RG. Sepsis care bundles and clinicians. Intensive Care Med. 2009;35:1149–51.
Fulbrook P, Mooney S. Care bundles in critical care: a practical approach to evidence-based practice. Nurs Crit Care. 2003;8(6):249–55.
Berenholtz SM, Dorman T, Ngo K, Provonost PJ. Qualitative review of intensive care unit quality indicators. J Crit Care. 2002;17:12–5.
McCannon CJ, Hackbarth AD, Griffin FA. Miles to go: an introduction to the 5 Million Lives Campaign. Jt Comm J Qual Patient Saf. 2007;33(8):477–84.
Institute for Healthcare Improvement. How-to guide: prevent ventilator-associated pneumonia. Cambridge, MA: Institute for Healthcare Improvement; 2012. www.IHI.org. Accessed 2 Jun 2014
Institute for Healthcare Improvement. How-to guide: prevent central line-associated bloodstream infections (CLABSI). Cambridge, MA: Institute for Healthcare Improvement; 2012. www.IHI.org. Accessed 2 Jun 2014
Resar R, Pronovost P, Haraden C, Simmonds T, Rainey T, Nolan T. Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. Jt Comm J Qual Patient Saf. 2005;31(5):243–8.
Furuya EY, Dick A, Perencevich EN, Pogorzelska M, Goldmann D, Stone PW. Central line bundle implementation in US intensive care units and impact on bloodstream infections. PLoS One. 2011;6(1):e15452.
Institute for Healthcare Improvement. IHI shares achievements of the 5 Million Lives Campaign. Cambridge, MA: Institute for Healthcare Improvement; 2008. http://www.ihi.org/about/news/Documents/IHIPressRelease_IHISharesAchievementsof5MillionLivesCampaign_Oct08.pdf. Accessed 2 Jun 2014.
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004;32:858–73.
Surviving sepsis campaign history. http://www.survivingsepsis.org/About-SSC/Pages/History.aspx. Accessed 3 Jul 2014.
Levy MM, Pronovost PJ, Dellinger RP, Townsend S, Resar RK, Clemmer TP, et al. Sepsis change bundles: converting guidelines into meaningful change in behavior and clinical outcome. Crit Care Med. 2004;32:S595–7.
Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, Schorr C, et al. The surviving sepsis campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med. 2010;38:367–74.
Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, et al. Surviving sepsis campaign: association between performance metrics and outcomes in a 7.5-year study. Crit Care Med. 2015;43(1):3–12.
Gao F, Melody T, Daniels DF, Giles S, Fox S. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis-prospective observational study. Crit Care. 2005;9:R764–70.
Zambon M, Ceola M, Almeida-de-Castro R, Gullo A, Vincent JL. Implementation of the surviving sepsis campaign guidelines for severe sepsis and septic shock: we could go faster. J Crit Care. 2008;23:455–60.
Chamberlain DJ, Willis EM, Bersten AB. The severe sepsis bundles as processes of care: a meta-analysis. Aust Crit Care. 2011;24:229–43.
Miller III RR, Dong L, Nelson NC, Brown SM, Kuttler KG, Probst DR, et al. Multicenter Implementation of a severe sepsis and septic shock treatment bundle. Am J Respir Crit Care Med. 2013;188:77–82.
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41:580–637.
Patel GP, Balk RA. Systemic steroids in severe sepsis and septic shock. Am J Respir Crit Care Med. 2012;185:133–9.
The NICE-SUGAR. Study Investigators (2009) intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009;360:1283–97.
Preiser JC, Devos P, Ruiz-Santana S, Mélot C, Annane D, Groeneveld J, et al. A prospective randomized multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the glucontrol study. Intensive Care Med. 2009;35:1738–48.
Ranieri VM, Thompson BT, Barie PS, Dhainaut JF, Douglas IS, Finfer S, et al. Drotrecogin alfa (activated) in adults with septic shock. N Engl J Med. 2012;366:2055–64.
Levy MM. The SSC improvement initiative: 2012 revised sepsis bundles. 42nd critical care congress review; 2013:9
Levy MM. The SSC improvement initiative: 2012 revised sepsis bundles. 42nd critical care congress review. 2013. https://www.youtube.com/watch?v=v08mYfxBJAE. Accessed 1 Sept 2014.
Amerling R, Winchester JF, Ronco C. Guidelines have done more harm than good. Blood Purif. 2008;26:73–6.
Camporota L, Brett S. Care bundles: implementing evidence or common sense. Crit Care. 2011;15:159–60.
Marik PE, Raghunathan K, Bloomstone J. Point/counterpoint: are the best patient outcomes achieved when ICU bundles are rigorously adhered to? No. Chest. 2013;144:374–8.
Dellinger RP, Townsend SR. Point/counterpoint: are the best patient outcomes achieved when ICU bundles are rigorously adhered to? Rebuttal. Chest. 2013;144:378–9.
Jones AE. Unbundling early sepsis resuscitation. Ann Emerg Med. 2014;63:654–5.
Marik PE, Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med. 2013;41:1774–81.
Dellinger RP, Townsend SR. Point/counterpoint: are the best patient outcomes achieved when ICU bundles are rigorously adhered to? Yes. Chest. 2013;144:372–4.
Surviving sepsis campaign statement regarding hemodynamic and oximetric monitoring in response to ProCESS and ARISE trials. http://www.survivingsepsis.org/Guidelines/Pages/default.aspx. Accessed 2 Oct 2014.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Evans, L., Bender, W. (2017). Bundled Therapies in Sepsis. In: Ward, N., Levy, M. (eds) Sepsis. Respiratory Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-48470-9_14
Download citation
DOI: https://doi.org/10.1007/978-3-319-48470-9_14
Published:
Publisher Name: Humana Press, Cham
Print ISBN: 978-3-319-48468-6
Online ISBN: 978-3-319-48470-9
eBook Packages: MedicineMedicine (R0)