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Stem Cell Therapy: Optimization, Regeneration, Reprogramming, Expansion, Tissue Engineering

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Abstract

A very brief overview on five important aspects of stem cell therapy are given in this chapter. The chapter is dealing with criteria for optimization of the pattern for cell-based therapies, extent of regeneration in animals and humans, nuclear reprogramming as a possible modality for treatment with pluripotent adult cells, significance of expansion, and essential role in Tissue Engineering.

Everything is theoretically impossible, until it is done.

Robert A. Heinlein

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References

  1. Al-Hajj M et al (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci 100(7):3983–3988

    Article  Google Scholar 

  2. Al-Sarraf M et al (1997) Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: an intergroup study. J Clin Onc 15(1):277–284

    Google Scholar 

  3. Brannon-Peppas L, James OB (2004) Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev 56(11):1649–1659

    Article  Google Scholar 

  4. Citron ML et al (2003) Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol 21(8):1431–1439

    Article  Google Scholar 

  5. Collins AT et al (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer research 65(23):10946–10951

    Google Scholar 

  6. Davis ME (2008) Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discovery 7(9):771–782

    Article  Google Scholar 

  7. Delaney G et al (2005) The role of radiotherapy in cancer treatment. Cancer 104(6):1129–1137

    Article  Google Scholar 

  8. Farokhzad OC et al (2004) Nanoparticle-aptamer bioconjugates a new approach for targeting prostate cancer cells. Cancer Res 64(21):7668–7672

    Article  Google Scholar 

  9. Fisher B et al (1988) Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-011. J Natl Cancer Inst 80(1):21–29

    Article  Google Scholar 

  10. Gagliardi G et al (1996) Long-term cardiac mortality after radiotherapy of breast cancer—application of the relative seriality model. Br J Radiol 69(825):839–846

    Article  Google Scholar 

  11. Gaitanis A and Stephen S (2010) Liposomal doxorubicin and nab-paclitaxel: nanoparticle cancer chemotherapy in current clinical use. Cancer Nanotechnol, 385–392

    Google Scholar 

  12. Gil J et al (2008) Cancer stem cells: the theory and perspectives in cancer therapy. J Appl Genet 49(2):193–199

    Article  Google Scholar 

  13. William JG et al (2005) Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 23(31):7794–7803

    Article  Google Scholar 

  14. Hillner BE, Smith TJ (1991) Efficiacy and cost effectiveness of adjuvant chemotherapy in women with node-negative breast cancer: a decision-analysis model. N Engl J Med 324(3):160–168

    Article  Google Scholar 

  15. Kirson ED et al (2004) Disruption of cancer cell replication by alternating electric fields. Cancer Res 64(9):3288–3295

    Article  Google Scholar 

  16. Chenwei L et al (2007) Identification of pancreatic cancer stem cells. Cancer Res 67(3):1030–1037

    Article  Google Scholar 

  17. Neve RM et al (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10(6):515–527

    Article  Google Scholar 

  18. Ramalho-Santos M et al (2002) Stemness: transcriptional profiling of embryonic and adult stem cells. Science 298(5593):597–600

    Article  Google Scholar 

  19. Reya T et al (2001) Stem cells, cancer, and cancer stem cells. Nature 414(6859):105–111

    Article  Google Scholar 

  20. Singh SK et al (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63(18):5821–5828

    Google Scholar 

  21. Stupp R et al (2012) NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality. Eur J Cancer 48(14):2192–220

    Google Scholar 

  22. Zipori D (2004) The nature of stem cells: state rather than entity. Nat Rev Genet 5(11):873–878

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Computer and Electrical Engineering, Florida Atlantic University, Boca Raton, Florida, USA

    Mirjana Pavlović

  2. Department of Life Sciences, Institute for Multidisciplinary Research, University of Belgrade, Belgrade, Serbia

    Ksenija Radotić

Authors
  1. Mirjana Pavlović
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  2. Ksenija Radotić
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Corresponding author

Correspondence to Mirjana Pavlović .

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© 2017 Springer International Publishing AG

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Pavlović, M., Radotić, K. (2017). Stem Cell Therapy: Optimization, Regeneration, Reprogramming, Expansion, Tissue Engineering. In: Animal and Plant Stem Cells. Springer, Cham. https://doi.org/10.1007/978-3-319-47763-3_16

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  • DOI: https://doi.org/10.1007/978-3-319-47763-3_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-47761-9

  • Online ISBN: 978-3-319-47763-3

  • eBook Packages: EngineeringEngineering (R0)

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