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Lumpy Skin Disease (Knopvelsiekte, Pseudo-Urticaria, Neethling Virus Disease, Exanthema Nodularis Bovis)

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Emerging and Re-emerging Infectious Diseases of Livestock

Abstract

Lumpy skin disease (LSD) is a notifiable acute viral disease of cattle that is endemic in most African countries and some of the Middle East countries. LSD currently poses a serious threat to Europe and the rest of the world. LSD is associated with high morbidity and low mortality in cattle. It causes serious economic losses due to severe reduction in milk production, feed intake, and weight conversion. The incubation period is reported to be between 1 and 4 weeks. Not all affected animals show clinical sings. High fever, lachrymation, and enlarged palpable lymph nodes are the first clinical signs reported. Soon after the fever, few to several variable-sized cutaneous nodules appear on different regions of the body. The entire body of the animal can be covered with nodules, and lesions may be seen in the mouth and nose as well as the mucous membranes of the eye in affected animals. In postmortem, pox lesions may be widespread and seen in each organ. Diagnosis of LSD is based on characteristic signs, histopathology, and virus isolation as well as polymerase chain reaction (PCR). In endemic regions, vaccination is the only effective method of control.

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Authors and Affiliations

  1. Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan

    Sameeh M. Abutarbush

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  1. Sameeh M. Abutarbush
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Correspondence to Sameeh M. Abutarbush .

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  1. INSERM, Paris, France

    Jagadeesh Bayry

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Abutarbush, S.M. (2017). Lumpy Skin Disease (Knopvelsiekte, Pseudo-Urticaria, Neethling Virus Disease, Exanthema Nodularis Bovis). In: Bayry, J. (eds) Emerging and Re-emerging Infectious Diseases of Livestock. Springer, Cham. https://doi.org/10.1007/978-3-319-47426-7_14

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