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Bilateral Regularization in Reproducing Kernel Hilbert Spaces for Discontinuity Preserving Image Registration

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Book cover Machine Learning in Medical Imaging (MLMI 2016)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 10019))

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Abstract

The registration of abdominal images is an increasing field in research and forms the basis for studying the dynamic motion of organs. Particularly challenging therein are organs which slide along each other. They require discontinuous transform mappings at the sliding boundaries to be accurately aligned. In this paper, we present a novel approach for discontinuity preserving image registration. We base our method on a sparse kernel machine (SKM), where reproducing kernel Hilbert spaces serve as transformation models. We introduce a bilateral regularization term, where neighboring transform parameters are considered jointly. This regularizer enforces a bias to homogeneous regions in the transform mapping and simultaneously preserves discontinuous magnitude changes of parameter vectors pointing in equal directions. We prove a representer theorem for the overall cost function including this bilateral regularizer in order to guarantee a finite dimensional solution. In addition, we build direction-dependent basis functions within the SKM framework in order to elongate the transformations along the potential sliding organ boundaries. In the experiments, we evaluate the registration results of our method on a 4DCT dataset and show superior registration performance of our method over the tested methods.

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Notes

  1. 1.

    https://github.com/ChristophJud/SKMImageRegistration.git.

  2. 2.

    Note that for \(d=3\), \(\mathcal {P}\) is the magnitude of the cross-product \(\Vert c_i \times c_j\Vert \).

  3. 3.

    http://www.creatis.insa-lyon.fr/rio/popi-model.

  4. 4.

    Target registration error: Euclidean distance between ground truth landmarks and reference landmarks which have been warped by the resulting f.

  5. 5.

    We defined the probability of a method \(H_a\) to beat the baseline \(H_0\) as \({P(X<Y)}\), where the independent random variables X and Y are distributed according to the Maxwell-Boltzmann distribution of the respective method \(H_a\) and \(H_0\).

References

  1. Gorbunova, V., Lo, P., Ashraf, H., Dirksen, A., Nielsen, M., de Bruijne, M.: Weight preserving image registration for monitoring disease progression in lung CT. In: Axel, L., Fichtinger, G., Metaxas, D., Székely, G. (eds.) MICCAI 2008, Part II. LNCS, vol. 5242, pp. 863–870. Springer, Heidelberg (2008)

    Chapter  Google Scholar 

  2. Hofmann, T., Schölkopf, B., Smola, A.J.: Kernel methods in machine learning. Ann. Stat. 36, 1171–1220 (2008)

    Article  MathSciNet  MATH  Google Scholar 

  3. Jud, C., Möri, N., Cattin, P.C.: Sparse kernel machines for discontinuous registration. In: 7th International Workshop on Biomedical Image Registration (2016)

    Google Scholar 

  4. Jud, C., Preiswerk, F., Cattin, P.C.: Respiratory motion compensation with topology independent surrogates. In: Workshop on Imaging and Computer Assistance in Radiation Therapy (2015)

    Google Scholar 

  5. Kiriyanthan, S., Fundana, K., Majeed, T., Cattin, P.C.: A primal-dual approach for discontinuity preserving image registration through motion segmentation. Int. J. Comput. Math. Methods Med. (2016, in press)

    Google Scholar 

  6. Möri, N., Jud, C., Salomir, R., Cattin, P.C.: Leveraging respiratory organ motion for non-invasive tumor treatment devices: a feasibility study. Phys. Med. Biol. 61(11), 4247–4267 (2016)

    Article  Google Scholar 

  7. Paciorek, C.J., Schervish, M.J.: Spatial modelling using a new class of nonstationary covariance functions. Environmetrics 17(5), 483–506 (2006)

    Article  MathSciNet  Google Scholar 

  8. Papież, B.W., Heinrich, M.P., Fehrenbach, J., Risser, L., Schnabel, J.A.: An implicit sliding-motion preserving regularisation via bilateral filtering for deformable image registration. Med. Image Anal. 18(8), 1299–1311 (2014)

    Article  Google Scholar 

  9. Rueckert, D., Sonoda, L.I., Hayes, C., Hill, D.L.G., Leach, M.O., Hawkes, D.J.: Nonrigid registration using free-form deformations: application to breast MR images. IEEE Trans. Med. Imaging 18(8), 712–721 (1999)

    Article  Google Scholar 

  10. Schmidt-Richberg, A.: Sliding motion in image registration. Registration Methods for Pulmonary Image Analysis, pp. 65–78. Springer, Wiesbaden (2014)

    Chapter  Google Scholar 

  11. Sotiras, A., Davatzikos, C., Paragios, N.: Deformable medical image registration: a survey. IEEE Trans. Med. Imaging 32(7), 1153–1190 (2013)

    Article  Google Scholar 

  12. Thirion, J.-P.: Image matching as a diffusion process: an analogy with Maxwell’s demons. Med. Image Anal. 2(3), 243–260 (1998)

    Article  Google Scholar 

  13. Vandemeulebroucke, J., Sarrut, D., Clarysse, P.: The POPI-model, a point-validated pixel-based breathing thorax model. In: International Conference on the Use of Computers in Radiation Therapy, vol. 2, pp. 195–199 (2007)

    Google Scholar 

  14. Vishnevskiy, V., Gass, T., Székely, G., Goksel, O.: Total variation regularization of displacements in parametric image registration. In: Yoshida, H., Näppi, J.J., Saini, S. (eds.) ABDI 2014. LNCS, vol. 8676, pp. 211–220. Springer, Heidelberg (2014)

    Google Scholar 

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Jud, C., Möri, N., Bitterli, B., Cattin, P.C. (2016). Bilateral Regularization in Reproducing Kernel Hilbert Spaces for Discontinuity Preserving Image Registration. In: Wang, L., Adeli, E., Wang, Q., Shi, Y., Suk, HI. (eds) Machine Learning in Medical Imaging. MLMI 2016. Lecture Notes in Computer Science(), vol 10019. Springer, Cham. https://doi.org/10.1007/978-3-319-47157-0_2

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  • DOI: https://doi.org/10.1007/978-3-319-47157-0_2

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