Imaging of Soft Tissue Tumors in the Pediatric Patient

  • Lennart JansEmail author
  • Koenraad L. Verstraete


Pediatric soft tissue tumors are rare. About 5 % of soft tissue tumors arise in utero and in young children (0–5 years) and only 7 % in children between 6 and 15 years old [1, 2].


Synovial Sarcoma Soft Tissue Tumor Malignant Peripheral Nerve Sheath Tumor Myositis Ossificans Alveolar Rhabdomyosarcoma 
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  1. 1.
    Kransdorf M (1995) Malignant soft tissue tumors in a large referral population: distribution of specific diagnoses by age, sex and location. Am J Roentgenol 164:129–134CrossRefGoogle Scholar
  2. 2.
    Kransdorf M (1995) Benign soft tissue tumors in a large referral population: distribution of specific diagnoses by age, sex and location. AJR Am J Roentgenol 164:395–402CrossRefPubMedGoogle Scholar
  3. 3.
    Murphey MD, Fairbairn KJ, Parman LM et al (1995) From the archives of the AFIP. Musculoskeletal angiomatous lesions: radiologic-pathologic correlation. Radiographics 15:893–917CrossRefPubMedGoogle Scholar
  4. 4.
    Sangkhathat S (2015) Current management of pediatric soft tissue sarcomas. World J Clin Pediatr 4:94–105CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Billings SD, Giblen G, Fanburg-Smith JC (2005) Superficial low-grade fibromyxoid sarcoma (Evans tumor): a clinicopathologic analysis of 19 cases with a unique observation in the pediatric population. Am J Surg Pathol 29(2):204–210CrossRefPubMedGoogle Scholar
  6. 6.
    Bisogno G, Sotti G, Nowicki Y et al (2004) Soft tissue sarcoma as a second malignant neoplasm in the pediatric age group. Cancer 100(8):1758–1765CrossRefPubMedGoogle Scholar
  7. 7.
    Bleyer WA (1993) What can be learned about childhood cancer from “Cancer statistics review 1973–1988”? Cancer 15:3229–3236CrossRefGoogle Scholar
  8. 8.
    Colon F, Upton J (1995) Pediatric hand tumors. Hand Clin 11:223–243. Conrad EU, Bradford L, Chansky HA (1996) Pediatric soft-tissue sarcomas. Orthop Clin North Am 27:655–664Google Scholar
  9. 9.
    De Maeseneer M, Vande Walle H, Lenchik L et al (1998) Subcutaneous granuloma annulare: MR imaging findings. Skeletal Radiol 27:215–217CrossRefPubMedGoogle Scholar
  10. 10.
    Fleming ID (1992) Staging of pediatric cancers. Semin Surg Oncol 8:94–97CrossRefPubMedGoogle Scholar
  11. 11.
    Fletcher BD, Hanna SL (1996) Pediatric musculoskeletal lesions simulating neoplasms. Magn Reson Imaging Clin N Am 4:721–747PubMedGoogle Scholar
  12. 12.
    Gallego MS, Millan JM, Gil-Martin R et al (1987) Juvenile hyalin fibromatosis: radiographic and pathologic findings of a new case. J Med Imaging 1:251–257Google Scholar
  13. 13.
    Garcia-Pena P, Mariscal A, Abellan C et al (1999) Juvenile xanthogranuloma with extracutaneous lesions. Pediatr Radiol 22:377–378CrossRefGoogle Scholar
  14. 14.
    Ha TV, Kleinman PK, Fraire A et al (1994) MR imaging of benign fatty tumors in children: report of four cases and review of the literature. Skeletal Radiol 23:361–367CrossRefPubMedGoogle Scholar
  15. 15.
    Harms D (2004) Soft tissue malignancies in childhood and adolescence. Pathological and clinical relevance based on data from the kiel pediatric tumor registry. Handchir Mikrochir Plast Chir 36(5):268–274CrossRefPubMedGoogle Scholar
  16. 16.
    Johnson GL, Baisden BL, Fishman EK (1997) Infantile myofibromatosis. Skeletal Radiol 26:611–614CrossRefPubMedGoogle Scholar
  17. 17.
    Laor T, Burrows PE (1998) Congenital anomalies and vascular birthmarks of the lower extremities. Magn Reson Imaging Clin N Am 6:497–519PubMedGoogle Scholar
  18. 18.
    Merton DA, Needleman L, Alexander AA et al (1992) Lipoblastoma: diagnosis with computed tomography, ultrasonography, and color Doppler imaging. J Ultrasound Med 11:549–552CrossRefPubMedGoogle Scholar
  19. 19.
    Meyer William H, Spunt Sheri L (2003) Soft tissue sarcomas of childhood. Cancer Treat Rev 30(3):269–280CrossRefGoogle Scholar
  20. 20.
    Upton J, Coombs C (1995) Vascular tumors in children. Hand Clin 11:307–337PubMedGoogle Scholar
  21. 21.
    Vazquez E, Enriquez G, Castellote A et al (1995) US, CT, and MR imaging of neck lesions in children. Radiographics 15:105–122CrossRefPubMedGoogle Scholar
  22. 22.
    Navarro OM, Laffan EE, Ngan B (2009) Pediatric soft-tissue tumors and pseudotumors: MR imaging features with pathologic correlation. Part 1. Imaging Approach, pseudotumors, vascular lesions, and adipocytic tumors. Radiographics 29:887–906CrossRefPubMedGoogle Scholar
  23. 23.
    Laffan EE, Ngan B, Navarro OM (2009) Pediatric soft-tissue tumors and pseudotumors: MR imaging features with pathologic correlation. Part 2. Tumors of fibroblastic/myofibroblastic, so-called fibrohistiocytic, muscular, lymphomatous, neurogenic, hair matrix, and uncertain origin. Radiographics 29(4):e36CrossRefPubMedGoogle Scholar
  24. 24.
    Ahn JM, Yoon HK, Suh YL et al (2000) Infantile fibromatosis in childhood: findings on MR imaging and pathologic correlation. Clin Radiol 55(1):19–24CrossRefPubMedGoogle Scholar
  25. 25.
    Navarro OM (2011) Soft tissue masses in children. Radiol Clin North Am 49:1235–1259CrossRefPubMedGoogle Scholar
  26. 26.
    Lawrence W Jr (1994) Soft tissue sarcomas in adults and children: a comparison. CA Cancer J Clin 44:197–199CrossRefPubMedGoogle Scholar
  27. 27.
    Brouns F, Stas M, De Wever I (2003) Delay in diagnosis of soft tissue sarcomas. Eur J Surg Oncol 29(5):440–445CrossRefPubMedGoogle Scholar
  28. 28.
    Ozbek SS, Arkun R, Killi R et al (1995) Image-directed color Doppler ultrasonography in the evaluation of superficial solid tumors. J Clin Ultrasound 23:233–238CrossRefPubMedGoogle Scholar
  29. 29.
    Yang WT, Ahuja A, Metreweli C (1997) Sonographic features of head and neck hemangiomas and vascular malformations: review of 23 patients. J Ultrasound Med 16:39–44CrossRefPubMedGoogle Scholar
  30. 30.
    Shapeero LG, Vanel D, Verstraete K, Bloem JL (1999) Dynamic contrast-enhanced MR imaging for soft tissue sarcomas. Semin Musculoskeletal Radiol 3:101–114CrossRefGoogle Scholar
  31. 31.
    Van der Woude HJ, Verstraete KL, Hogendoorn PC et al (1998) Musculoskeletal tumors: does fast dynamic contrast-enhanced subtraction MR imaging contribute to the characterization? Radiology 208:821–828CrossRefPubMedGoogle Scholar
  32. 32.
    De Schepper A, Ramon F, Degryse H (1992) Statistical analysis of MRI parameters predicting malignancy in 141 soft tissue masses. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 156:587–591CrossRefPubMedGoogle Scholar
  33. 33.
    Berquist T, Ehman R, King B et al (1990) Value of MR imaging in differentiating benign from malignant soft tissue masses: study of 95 lesions. AJR Am J Roentgenol 155:1251–1255CrossRefPubMedGoogle Scholar
  34. 34.
    Crim J, Seeger L, Yao L et al (1992) Diagnosis of soft tissue masses with MR imaging: can benign masses be differentiated from malignant ones? Radiology 185:581–586CrossRefPubMedGoogle Scholar
  35. 35.
    Moulton J, Blebea J, Dunco D et al (1995) MR imaging of soft tissue masses: diagnostic efficacy and value of distinguishing between benign and malignant lesions. AJR Am J Roentgenol 164:1191–1199CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Radiology and Nuclear Medicine and Faculty of Medicine and Health SciencesGhent UniversityGentBelgium

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