Fibroblastic/Myofibroblastic Tumors

  • Jan E. VandevenneEmail author
  • Arthur M. De Schepper


Fibroblastic/myofibroblastic tumors represent a very large subset of mesenchymal tumors. Diagnosis relies on histopathology often with additional immunohistochemic and genetic testing. Some benign lesions such as elastofibroma, fibromatosis colli, ischemic fasciitis and nuchal fibroma can be recognized by the radiologist combining specific imaging findings with location, clinical history and age of the patient. Other benign lesions such as myositis ossificans, nodular fasciitis, proliferative fasciitis and proliferative myositis may have a pseudosarcomatous appearance and follow-up exams demonstrating size reduction and increase of the T2-hypointense collagenous parts or ossification (tumor involution/maturation) are an essential part of the diagnostic process. The role of imaging for aggressive fibromatosis, other intermediate and malignant tumors mainly consists of defining tumor size, location and infiltration of neighbouring tissues, and post treatment follow up.


Desmoid Tumor Solitary Fibrous Tumor Tendon Sheath Inflammatory Myofibroblastic Tumor Myositis Ossificans 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The current revision of this chapter is gratefully dedicated to the memory of Professor Arthur De Schepper (November 30, 1937–October 4, 2013).


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of RadiologyZiekenhuis Oost LimburgGenkBelgium

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