How Do Interconnected Neuronal Networks Adjust to External Stimulation: Parametric Studies of DBS-FMRI

  • Javier Moya
  • Daniel Torres
  • David Moratal
  • Santiago CanalsEmail author
Conference paper
Part of the Biosystems & Biorobotics book series (BIOSYSROB, volume 15)


The use of intracranial electrical microstimulation for the treatment of neurologic and psychiatric disorders, as well as in neural prosthesis, has experienced an exponential growth in the last decade. Despite this spectacular expansion and the great promise of some applications, little is known about the precise neurobiological mechanisms underlying its actions, the rules governing activity propagation during stimulation and the probable roles obeyed by short and long-term plasticity processes in the synapses being activated. We combine deep brain electric microstimulation and functional magnetic resonance imaging (fMRI) to investigate local and brain-wide functional networks activated by different sets of stimulation parameters that produced distinct behavioral effects.


Transcranial Magnetic Stimulation Deep Brain Stimulation Functional Connectivity Brain Network Stimulation Protocol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We are grateful to Begoña Fernández for her excellent technical assistance.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Javier Moya
    • 1
  • Daniel Torres
    • 2
  • David Moratal
    • 1
  • Santiago Canals
    • 2
    Email author
  1. 1.Center for Biomaterials and Tissue EngineeringUniversitat Politècnica de ValènciaValenciaSpain
  2. 2.Instituto de NeurocienciasConsejo Superior de Investigaciones Científicas and Universidad Miguel HernándezSant Joan d’AlacantSpain

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