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Hyperhidrosis and Stress

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Stress and Skin Disorders

Abstract

Hyperhidrosis is a psychological skin condition characterized by uncontrollable, excessive amounts of sweat in specific body locations. Although not a physically debilitating condition, those individuals affected with this condition commonly experience psychosocial stress during regular social encounters and exhibit low self-confidence, thus drastically decreasing the quality of life of these individuals (Coutinho dos Santos et al. Pediatr Dermatol 26(4):439–444, 2009; Glogau, Dermatol Surg 24(8):817–819, 1998; Kouris et al. Pediatr Dermatol 32(2):226–230, 2015). Hyperhidrosis is often diagnosed in patients suffering from psychosocial disorders such as social anxiety, suggesting a psychological factor may influence it’s onset. Various management options exist for the treatment of hyperhidrosis including fractionated microneedle radio (FMR) treatment, botulinum toxin type A (BTXA), surgery, oral administration of the anticholinergic drug glycopyrronium bromide (glycopyrrolate), aluminum chloride antiperspirants, iontophoresis, and endoscopic thoracic sympathectomy (Glogau, Dermatol Surg 24(8):817–819, 1998; Kouris et al. Pediatr Dermatol 32(2):226–230, 2015; Bajaj and Langtry, Br J Dermatol 157(1):118–121, 2007; Fatemi Naeini et al. Australas J Dermatol 56(4):279–284, 2015; Kobayashi et al. J Dermatol 21(8):575–581, 1994; Rompel and Scholz, J Eur Acad Dermatol Venereol 15(3):207–211, 2001). Currently, endoscopic thoracic sympathectomy is the only current, permanent treatment option. However, new therapeutic options on the horizon such as lasers and microwave thermolysis demonstrate promising results.

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Abbreviations

ACTH:

Adrenocorticotropic hormone

BTXA:

Botulinum toxin type A

CRH:

Corticotrophin-releasing hormone

DLQI:

Dermatology Life Quality Index

HADS:

Hospital Anxiety and Depression Scale

HDSS:

Hyperhidrosis Disease Severity Scale

HPA:

Hypothalamic-pituitary-adrenal

MMPI-2:

Minnesota Multiphasic Personality Inventory-2

OCD:

Obsessive-compulsive disorder

ORS:

Olfactory reference syndrome

PAH:

Primary axillary hyperhidrosis

SES:

Subjective evaluation scale

VAS:

Visual Analogue Scale

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Correspondence to Keyvan Nouri MD .

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Hsu, V.M., Shah, V.V., Aldahan, A.S., Mlacker, S., Samarkandy, S., Nouri, K. (2017). Hyperhidrosis and Stress. In: França, K., Jafferany, M. (eds) Stress and Skin Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-46352-0_14

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  • DOI: https://doi.org/10.1007/978-3-319-46352-0_14

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