Skip to main content

The Imported Fire Ant: The US Experience

  • Chapter
  • First Online:
Stinging Insect Allergy

Abstract

Referrals for imported fire ant (IFA) hypersensitivity account for the majority of referrals to venom clinics in endemic areas in the USA. Since importation into the USA almost 100 years ago, the IFA (Solenopsis invicta, the red IFA, and Solenopsis richteri, the black IFA) have expanded to both coasts of the USA as they wreak havoc upon the people and agriculture of the southern parts of the nation. With high annual sting attack rates among those dwelling in endemic sites, rapid identification and treatment of those with hypersensitivity is critical. Immunotherapy with IFA whole-body extract is safe and effective. Both conventional and rush schedules have been utilized to achieve maintenance therapy doses similar to therapy seen with the flying Hymenoptera. This chapter provides information about IFA and the evaluation and management of those individuals experiencing hypersensitivity reactions to IFA stings.

The views expressed are those of the authors and do not reflect the official views or policy of the Department of Defense or its Components.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ascunce MS, Yang CC, Oakey J, Calcaterra L, Wu WJ, Shih CJ, et al. Global invasion history of the fire ant Solenopsis invicta. Science. 2011;331(6020):1066–8. doi:10.1126/science.1198734.

    Article  CAS  PubMed  Google Scholar 

  2. Lofgren CS, Banks WA, Glancey BM. Biology and control of imported fire ants. Annu Rev Entomol. 1975;20:1–30.

    Article  CAS  PubMed  Google Scholar 

  3. Caldera EJ, Ross KG, DeHeer CJ, Shoemaker DD. Putative native source of the invasive fire ant Solenopsis invicta in the USA. Biol Invasions. 2008;10(8):1457–79. doi:10.1007/s10530-008-9219-0.

    Article  Google Scholar 

  4. Brown CL. Imported fire ants. In: Animal and plant health inspection service. United States Department of Agriculture;2015. https://www.aphis.usda.gov/wps/portal/aphis/ourfocus/planthealth/sa_domestic_pests_and_diseases/sa_pests_and_diseases/sa_insects/sa_fire_ants. Accessed 4 Nov 2015.

  5. Kemp SF, deShazo RD, Moffitt JE, Williams DF, Buhner 2nd WA. Expanding habitat of the imported fire ant (Solenopsis invicta): a public health concern. J Allergy Clin Immunol. 2000;105(4):683–91.

    Article  CAS  PubMed  Google Scholar 

  6. Stafford CT. Hypersensitivity to fire ant venom. Ann Allergy Asthma Immunol. 1996;77(2):87–95.

    Article  CAS  PubMed  Google Scholar 

  7. Hoffman DR. Ant venoms. Curr Opin Allergy Clin Immunol. 2010;10(4):342–6. doi:10.1097/ACI.0b013e328339f325.

    Article  CAS  PubMed  Google Scholar 

  8. Tracy JM, Demain JG, Quinn JM, Hoffman DR, Goetz DW, Freeman TM. The natural history of exposure to the imported fire ant (Solenopsis invicta). J Allergy Clin Immunol. 1995;95(4):824–8.

    Article  CAS  PubMed  Google Scholar 

  9. Partridge ME, Blackwood W, Hamilton RG, Ford J, Young P, Ownby DR. Prevalence of allergic sensitization to imported fire ants in children living in an endemic region of the southeastern United States. Ann Allergy Asthma Immunol. 2008;100(1):54–8. doi:10.1016/S1081-1206(10)60405-X.

    Article  CAS  PubMed  Google Scholar 

  10. Caplan EL, Ford JL, Young PF, Ownby DR. Fire ants represent an important risk for anaphylaxis among residents of an endemic region. J Allergy Clin Immunol. 2003;111(6):1274–7.

    Article  PubMed  Google Scholar 

  11. Caplan EL, Ford JL, Young PF, Ownby DR. Prevalence of allergic sensitivity to imported fire ants in children from an endemic region. J Allergy Clin Immunol. 2004;113(Suppl 2):S74.

    Article  Google Scholar 

  12. Johnson T, Dietrich J, Hagan L. Management of stinging insect hypersensitivity: a 5-year retrospective medical record review. Ann Allergy Asthma Immunol. 2006;97(2):223–5.

    Article  PubMed  Google Scholar 

  13. Freeman TM. Hymenoptera hypersensitivity in an imported fire ant endemic area. Ann Allergy Asthma Immunol. 1997;78(4):369–72.

    Article  CAS  PubMed  Google Scholar 

  14. Bhutani S, Khan DA. Allergist referrals for systemic reactions to imported fire ants: a community survey in an endemic area. Ann Allergy Asthma Immunol. 2009;102(2):145–8. doi:10.1016/S1081-1206(10)60245-1.

    Article  PubMed  Google Scholar 

  15. Nguyen SA, Napoli DC. Natural history of large local and generalized cutaneous reactions to imported fire ant stings in children. Ann Allergy Asthma Immunol. 2005;94(3):387–90.

    Article  PubMed  Google Scholar 

  16. Stafford CT, Hutto LS, Rhoades RB, Thompson WO, Impson LK. Imported fire ant as a health hazard. South Med J. 1989;82(12):1515–9.

    Article  CAS  PubMed  Google Scholar 

  17. Rhoades RB, Stafford CT, James Jr FK. Survey of fatal anaphylactic reactions to imported fire ant stings. Report of the fire ant Subcommittee of the American Academy of Allergy and immunology. J Allergy Clin Immunol. 1989;84(2):159–62.

    Article  CAS  PubMed  Google Scholar 

  18. Rupp MR, deShazo RD. Indoor fire ant sting attacks: a risk for frail elders. Am J Med Sci. 2006;331(3):134–8.

    Article  PubMed  Google Scholar 

  19. deShazo RD, Williams DF, Moak ES. Fire ant attacks on residents in health care facilities: a report of two cases. Ann Intern Med. 1999;131(6):424–9.

    Article  CAS  PubMed  Google Scholar 

  20. More DR, Kohlmeier RE, Hoffman DR. Fatal anaphylaxis to indoor native fire ant stings in an infant. Am J Forensic Med Pathol. 2008;29(1):62–3.

    Article  PubMed  Google Scholar 

  21. Golden DB, Moffitt J, Nicklas RA, Freeman T, Graft DF, Reisman RE, et al. Stinging insect hypersensitivity: a practice parameter update 2011. J Allergy Clin Immunol. 2011;127(4):852–4. e1-23 doi:10.1016/j.jaci.2011.01.025.

    Article  PubMed  Google Scholar 

  22. Rans TS, Hrabak TM, Whisman BA, Grier TJ, LeFevre DM, Kwon PO, et al. Compatibility of imported fire ant whole body extract with cat, ragweed, Dermatophagoides pteronyssinus, and timothy grass allergens. Ann Allergy Asthma Immunol. 2009;102(1):57–61. doi:10.1016/S1081-1206(10)60109-3.

    Article  PubMed  Google Scholar 

  23. Goddard J. Personal protection measures against fire ant attacks. Ann Allergy Asthma Immunol. 2005;95(4):344–9.

    Article  PubMed  Google Scholar 

  24. Freeman TM, Hylander R, Ortiz A, Martin ME. Imported fire ant immunotherapy: effectiveness of whole body extracts. J Allergy Clin Immunol. 1992;90(2):210–5.

    Article  CAS  PubMed  Google Scholar 

  25. Tankersley MS, Walker RL, Butler WK, Hagan LL, Napoli DC, Freeman TM. Safety and efficacy of an imported fire ant rush immunotherapy protocol with and without prophylactic treatment. J Allergy Clin Immunol. 2002;109(3):556–62.

    Article  PubMed  Google Scholar 

  26. Judd CA, Parker AL, Meier EA, Tankersley MS. Successful administration of a 1-day imported fire ant rush immunotherapy protocol. Ann Allergy Asthma Immunol. 2008;101(3):311–5. doi:10.1016/S1081-1206(10)60497-8.

    Article  PubMed  Google Scholar 

  27. Dietrich JJ, Moore LM, Nguyen S, Hagan LL, Tankersley MS. Imported fire ant hypersensitivity: a 1-day rush immunotherapy schedule without premedication. Ann Allergy Asthma Immunol. 2009;103(6):535–6. doi:10.1016/S1081-1206(10)60271-2.

    Article  PubMed  Google Scholar 

  28. Arseneau AM, Nesselroad TD, Dietrich JJ, Moore LM, Nguyen S, Hagan LL, et al. A 1-day imported fire ant rush immunotherapy schedule with and without premedication. J Allergy Clin Immunol. 2013;111(6):562–6. doi:10.1016/j.anai.2013.08.021.

    Google Scholar 

  29. La Shell MS, Calabria CW, Quinn JM. Imported fire ant field reaction and immunotherapy safety characteristics: the IFACS study. J Allergy Clin Immunol. 2010;125(6):1294–9. doi:10.1016/j.jaci.2010.02.041.

    Article  PubMed  Google Scholar 

  30. Tille KS, Parker AL. Imported fire ant rush desensitization using omalizumab and a premedication regimen. Ann Allergy Asthma Immunol. 2014;113(5):571–88. doi:10.1016/j.anai.2014.08.007.

    Article  Google Scholar 

  31. Tartibi HM, Majmundar AR, Khan DA. Successful use of omalizumab for prevention of fire ant anaphylaxis. J Allergy Clin Immunol. 2010;126(3):664–5. doi:10.1016/j.jaci.2010.06.014.

    Article  PubMed  Google Scholar 

  32. Stokes SC, Quinn JM, Sacha JJ, White KM. Adherence to imported fire ant subcutaneous immunotherapy. Ann Allergy Asthma Immunol. 2013;110(3):165–7. doi:10.1016/j.anai.2012.11.010.

    Article  PubMed  Google Scholar 

  33. Quinn JM, Tajiri KS, Motta P, Freeman TM. Long-term efficacy after discontinuation of imported fire ant (Solenopsis invicta) immunotherapy. J Allergy Clin Immunol. 1994;93(Suppl 1):S223.

    Google Scholar 

  34. Forester JP, Johnson TL, Arora R, Quinn JM. Systemic reaction rates to field stings among imported fire ant-sensitive patients receiving >3 years of immunotherapy versus <3 years of immunotherapy. Allergy Asthma Proc. 2007;28(4):485–8.

    Article  PubMed  Google Scholar 

  35. Lee JK, Betschel SD. A case of the first documented fire ant anaphylaxis in Canada. Allergy Asthma Clin Immunol. 2013;9(1):25. doi:10.1186/1710-1492-9-25.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Groden E, Drummond FA, Garnas J, Franceour A. Distribution of an invasive ant, Myrmica rubra (hymenoptera: Formicidae), in Maine. J Econ Entomol. 2005;98(6):1774–84.

    Article  PubMed  Google Scholar 

  37. Arevalo HA, Groden E. European fire ant, red ant (suggested common names), Myrmica rubra Linnaeus (Insecta: Hymenoptera: Formicidae: Myrmicinae). In: University of Florida, Institute of Food and Agricultural Sciences, Florida Cooperative Extension Publication EENY-410. 2007. http://entomology.ifas.ufl.edu/creatures. Accessed 23 Oct 2015.

  38. Bolton B. An online catalog of the ants of the world. 2014. http://www.antcat.org/catalog/429752. Accessed 18 Oct 2015.

  39. LeBrun EG, Abbott J, Gilbert LE. Imported crazy ant displaces imported fire ant, reduces and homogenizes grassland ant and arthropod assemblages. Biol Invasions. 2013;15:2429–42. doi:10.1007/s10530-013-0463-6.

    Article  Google Scholar 

  40. Lebrun EG, Jones NT, Gilbert LE. Chemical warfare among invaders: a detoxification interaction facilitates an ant invasion. Science. 2014;343:1014–7. doi:10.1126/science.1245833.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Steigelman M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Tankersley, M., Steigelman, D. (2017). The Imported Fire Ant: The US Experience. In: Freeman, T., Tracy, J. (eds) Stinging Insect Allergy. Springer, Cham. https://doi.org/10.1007/978-3-319-46192-2_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-46192-2_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46190-8

  • Online ISBN: 978-3-319-46192-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics