Regulation of Dietary Nitrate and Nitrite: Balancing Essential Physiological Roles with Potential Health Risks

  • Norman G. HordEmail author
  • Melissa N. Conley
Part of the Nutrition and Health book series (NH)


Human consumption of dietary nitrate and nitrite is controversial. Exposure through processed meats is associated with gastrointestinal cancer risk while consumption of nitrate from plant food sources, the source of over 80 % of human nitrate consumption, is associated with potential cardiovascular benefits. Identifying the physiological contexts in which dietary nitrate and nitrite produce health benefits and risks is necessary for clear guidance regarding dietary consumption of nitrate-containing foods. Development and application of nitrate and nitrite concentrations in national food databases will assist scientists and regulatory agencies in addressing these questions in prospective epidemiological studies.


Accepted daily intake Dietary recommendations World Health Organization Food safety Risk benefit evaluation 


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.School of Biological and Population Health SciencesOregon State UniversityCorvallisUSA

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