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Vascular Diseases for the Non-Specialist pp 35–45Cite as

Atherosclerosis

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Abstract

Atherosclerosis is a chronic inflammatory disease of multifactorial origin that occurs in response to endothelial aggression, affecting mainly the intima of medium and large caliber arteries. It is usually consequent to traditional risk factors such as diabetes mellitus, hypertension, dyslipidemia, obesity and smoking. It is related with several cardiovascular morbidities such as cerebrovascular disease, coronary, peripheral arterial and renovascular diseases. According to the World Health Organization, cardiovascular disease is the main cause of disability and premature death worldwide. An estimated 17.5 million people died from this cause in 2005, representing 30 % of all deaths in the world. This can be explained by understanding that people are more exposed to risk factors and less exposed to prevent efforts. Atherosclerosis prevention is less costly than treating its complications; thus, identification of subclinical disease in the asymptomatic phase has emerged as a public health and economic imperative.

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Author information

Authors and Affiliations

  1. Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190. Santa Efigênia, Belo Horizonte, Minas Gerais, 30130-100, Brazil

    Camila Silva Coradi M.D., Bruno Henrique Alvarenga M.D. & Gilberto Zulato Chaves Figueiredo M.D.

  2. Division of Vascular and Endovascular Surgery, Department of Surgery, Escola Paulista de Medicina da Universidade Federal de São Paulo, Rua Borges Lagoa, 754, Sao Paulo, Sao Paulo, 04038-001, Brazil

    Carolina Dutra Queiroz Flumignan M.D. & Ronald Luiz Gomes Flumignan M.D., Ph.D.

  3. Geriatric Division, Department of Medicine, Escola Paulista de Medicina da Universidade Federal de São Paulo, Rua Professor Francisco de Castro, 105, Sao Paulo, Sao Paulo, 04020-050, Brazil

    Renato Laks M.D.

Authors
  1. Camila Silva Coradi M.D.
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  2. Carolina Dutra Queiroz Flumignan M.D.
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  3. Renato Laks M.D.
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  4. Ronald Luiz Gomes Flumignan M.D., Ph.D.
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  5. Bruno Henrique Alvarenga M.D.
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Correspondence to Camila Silva Coradi M.D. .

Editor information

Editors and Affiliations

  1. Department of Vascular Surgery, Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

    Tulio Pinho Navarro

  2. Yale Univ School Medicine, New Haven, Connecticut, USA

    Alan Dardik

  3. Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

    Daniela Junqueira

  4. Universidade Federal de Minas Gerais, Belo Horizone, Minas Gerais, Brazil

    Ligia Cisneros

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Coradi, C.S., Flumignan, C.D.Q., Laks, R., Flumignan, R.L.G., Alvarenga, B.H., Figueiredo, G.Z.C. (2017). Atherosclerosis. In: Navarro, T., Dardik, A., Junqueira, D., Cisneros, L. (eds) Vascular Diseases for the Non-Specialist. Springer, Cham. https://doi.org/10.1007/978-3-319-46059-8_3

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  • DOI: https://doi.org/10.1007/978-3-319-46059-8_3

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