Abstract
Resilience is an individual’s ability to maintain or regain mental health despite adversity; this is a dynamic process that may begin as early as conception. Early on, brain development is guided by the interactions of genes and experience, and an individual’s response to environmental insults can be influenced in a gene-by-environmental interaction. Adverse or positive early childhood experiences (ACE’s) can lead to biological embedding. Resilience is very likely to be influenced by genes and upbringing as well as other biological, psychological, and social interactions. Adolescent behaviors including bullying and dating violence may affect one’s resilience, and adolescent substance abuse may be indicative of a resilience issue.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsSources
Alves E, Fiedler A, Ghabriel N, et al. Early social environment affects the endogenous oxytocin system: a review and future directions. Front Endocrinol. 2015;6:32.
Caspi A, Sugden K, Moffitt T, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science. 2003;301:386–9.
Comasco E, Gustafsson P, Sydsjo G, et al. Psychiatric symptoms in adolescents: FKBP5 genotype-early life adversity interaction effects. Eur Child Adolesc Psychiatry. 2015;24:1473–83.
Feder A, Nestler E, Charney D. Psychobiology and molecular genetics of resilience. Nat Rev Neurosci. 2009;10:446–51.
Felitti V, Anda R, Nordenberg D, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. Am J Prev Med. 1998;14:245–58.
Fries A, Ziegler T, Kurian J, et al. Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior. Proc Natl Acad Sci U S A. 2005;102:17237–40.
Herrman H, Stewart D, Diaz-Granados N, et al. What is resilience? Can J Psychiatry. 2011;56:258–64.
Karatsoreos I, McEwen B. Annual research review: the neurobiology and physiology of resilience and adaptation across the life course. J Child Psychol Psychiatry. 2013;54:337–47.
Merikangas K, He J, Burstein M, et al. Lifetime prevalence of mental disorders in US adolescents: results from the National Comorbidity Study-Adolescent Supplement (NCS-A). J Am Acad Child Adolesc Psychiatry. 2010;49:980–9.
Nelson C. A neurobiological perspective on early human deprivation. Child Dev Perspect. 2007;1:13–8.
Nelson C, Bos K, Gunmar M, et al. The neurobiological toll of early human deprivation. Monogr Soc Res Child Dev. 2011;76:127–46.
Rutter M. Annual research review: resilience-clinical implications. J Child Psychol Psychiatry. 2012;54:474–87.
Voelimin A, Winsaeler K, Hug E, et al. Blunted endocrine and cardiovascular: reactivity in young health women reporting a history of childhood adversity. Psychoneuroendocrinology. 2015;51:58–67.
Yehuda R, Flory J, Pratchett L, et al. Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. Psychopharmacology. 2010;212:405–17.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Goldstein, M.A. (2017). Nature, Nurture, Adolescents, and Resilience. In: Goldstein, M. (eds) The MassGeneral Hospital for Children Adolescent Medicine Handbook. Springer, Cham. https://doi.org/10.1007/978-3-319-45778-9_28
Download citation
DOI: https://doi.org/10.1007/978-3-319-45778-9_28
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-45777-2
Online ISBN: 978-3-319-45778-9
eBook Packages: MedicineMedicine (R0)