Skip to main content

Predisposing Factors for Onychomycosis

  • Chapter
  • First Online:
Onychomycosis

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Summerbell RC, Kane J, Krajden S. Onychomycosis, tinea pedis and tinea manuum caused by non-dermatophytic filamentous fungi. Mycoses. 1989;32(12):609–19.

    Article  CAS  PubMed  Google Scholar 

  2. Caputo R, De Boulle K, Del Rosso J, Nowicki R. Prevalence of superficial fungal infections among sports-active individuals: results from the Achilles survey, a review of the literature. J Eur Acad Dermatol Venereol (JEADV). 2001;15(4):312–6.

    CAS  Google Scholar 

  3. Elewski BE, Charif MA. Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions. Arch Dermatol. 1997;133(9):1172–3.

    Article  CAS  PubMed  Google Scholar 

  4. Heikkila H, Stubb S. The prevalence of onychomycosis in Finland. Br J Dermatol. 1995;133(5):699–703.

    Article  CAS  PubMed  Google Scholar 

  5. Sais G, Jucgla A, Peyri J. Prevalence of dermatophyte onychomycosis in Spain: a cross-sectional study. Br J Dermatol. 1995;132(5):758–61.

    Article  CAS  PubMed  Google Scholar 

  6. Ghannoum MA, Hajjeh RA, Scher R, et al. A large-scale North American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns. J Am Acad Dermatol. 2000;43(4):641–8.

    Article  CAS  PubMed  Google Scholar 

  7. Pierard G. Onychomycosis and other superficial fungal infections of the foot in the elderly: a pan-European survey. Dermatology. 2001;202(3):220–4.

    Article  CAS  PubMed  Google Scholar 

  8. Elewski BE, Tosti A. Risk factors and comorbidities for onychomycosis: implications for treatment with topical therapy. J Clin Aesthet Dermatol. 2015;8(11):38–42.

    PubMed  PubMed Central  Google Scholar 

  9. Belyayeva E, Gregoriou S, Chalikias J, et al. The impact of nail disorders on quality of life. Eur J Dermatol (EJD). 2013;23(3):366–71.

    Google Scholar 

  10. Schein JR, Gause D, Stier DM, Lubeck DP, Bates MM, Fisk R. Onychomycosis. Baseline results of an observational study. J Am Podiatr Med Assoc. 1997;87(11):512–9.

    Article  CAS  PubMed  Google Scholar 

  11. Milobratovic D, Jankovic S, Vukicevic J, Marinkovic J, Jankovic J, Railic Z. Quality of life in patients with toenail onychomycosis. Mycoses. 2013;56(5):543–51.

    Article  PubMed  Google Scholar 

  12. Papini M, Piraccini BM, Difonzo E, Brunoro A. Epidemiology of onychomycosis in Italy: prevalence data and risk factor identification. Mycoses. 2015;58(11):659–64.

    Article  PubMed  Google Scholar 

  13. Sigurgeirsson B, Steingrimsson O. Risk factors associated with onychomycosis. J Eur Acad Dermatol Venereol (JEADV). 2004;18(1):48–51.

    Article  CAS  Google Scholar 

  14. Polat M, Ilhan MN. Dermatological complaints of the elderly attending a dermatology outpatient clinic in Turkey: a prospective study over a one-year period. Acta Dermatovenerol Croat (ADC). 2015;23(4):277–81.

    Google Scholar 

  15. Deo MS, Kerse N, Vandal AC, Jarrett P. Dermatological disease in the older age group: a cross-sectional study in aged care facilities. BMJ Open. 2015;5(12):e009941.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Gupta AK, Sibbald RG, Lynde CW, et al. Onychomycosis in children: prevalence and treatment strategies. J Am Acad Dermatol. 1997;36(3 Pt 1):395–402.

    Article  CAS  PubMed  Google Scholar 

  17. Gupta C, Das S, Ramachandran VG, et al. Possible role of trichophytin antigen in inducing impaired immunological clearance of fungus in onychomycosis. Mycopathologia. 2016;181(3–4):247–51.

    Article  CAS  PubMed  Google Scholar 

  18. Tosti A, Hay R, Arenas-Guzman R. Patients at risk of onychomycosis–risk factor identification and active prevention. J Eur Acad Dermatol Venereol (JEADV). 2005;19(Suppl 1):13–6.

    Article  Google Scholar 

  19. Zaias N, Tosti A, Rebell G, et al. Autosomal dominant pattern of distal subungual onychomycosis caused by Trichophyton rubrum. J Am Acad Dermatol. 1996;34(2 Pt 1):302–4.

    Article  CAS  PubMed  Google Scholar 

  20. English MP. Trichophyton rubrum infection in families. Br Med J. 1957;1(5021):744–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Many H, Derbes VJ, Friedman L. Trichophyton rubrum: exposure and infection within household groups. Arch Dermatol. 1960;82:226–9.

    Article  CAS  PubMed  Google Scholar 

  22. Zaitz C, Campbell I, Moraes JR, et al. HLA-associated susceptibility to chronic onychomycosis in Brazilian Ashkenazic Jews. Int J Dermatol. 1996;35(9):681–2.

    Article  CAS  PubMed  Google Scholar 

  23. Asz-Sigall D, Lopez-Garcia L, Vega-Memije ME, et al. HLA-DR6 association confers increased resistance to T. rubrum onychomycosis in Mexican Mestizos. Int J Dermatol. 2010;49(12):1406–9.

    Article  PubMed  Google Scholar 

  24. Svejgaard E, Jakobsen B, Svejgaard A. HLA studies in chronic dermatophytosis caused by Trichophyton rubrum. Acta Derm Venereol. 1983;63(3):254–5.

    CAS  PubMed  Google Scholar 

  25. Zuccarello D, Salpietro DC, Gangemi S, et al. Familial chronic nail candidiasis with ICAM-1 deficiency: a new form of chronic mucocutaneous candidiasis. J Med Genet. 2002;39(9):671–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Ferwerda B, Ferwerda G, Plantinga TS, et al. Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med. 2009;361(18):1760–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Gupta AK, Konnikov N, MacDonald P, et al. Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey. Br J Dermatol. 1998;139(4):665–71.

    Article  CAS  PubMed  Google Scholar 

  28. Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. Int J Dermatol. 2002;41(10):647–51.

    Article  PubMed  Google Scholar 

  29. Elbendary A, El Tawdy A, Zaki N, Alfishawy M, Rateb A. Subclinical onychomycosis in patients with type II diabetes. Dermatol Reports. 2015;7(3):6099.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Papini M, Cicoletti M, Fabrizi V, Landucci P. Skin and nail mycoses in patients with diabetic foot. G Ital Dermatol Venereol (Organo ufficiale, Societa italiana di dermatologia e sifilografia). 2013;148(6):603–8.

    CAS  Google Scholar 

  31. Wijesuriya TM, Kottahachchi J, Gunasekara TD, et al. Aspergillus species: an emerging pathogen in onychomycosis among diabetics. Indian J Endocrinol Metab. 2015;19(6):811–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Vlahovic TC, Joseph WS. Efinaconazole topical, 10 % for the treatment of toenail onychomycosis in patients with diabetes. J Drugs Dermatol (JDD). 2014;13(10):1186–90.

    CAS  Google Scholar 

  33. Gupta AK, Taborda P, Taborda V, et al. Epidemiology and prevalence of onychomycosis in HIV-positive individuals. Int J Dermatol. 2000;39(10):746–53.

    Article  CAS  PubMed  Google Scholar 

  34. Cribier B, Mena ML, Rey D, et al. Nail changes in patients infected with human immunodeficiency virus. A prospective controlled study. Arch Dermatol. 1998;134(10):1216–20.

    Article  CAS  PubMed  Google Scholar 

  35. Gianni C, Cerri A, Capsoni F, Ongari AM, Rossini P, Crosti C. Recurrent proximal white subungual onychomycosis associated with a defect of the polymorphonuclear chemotaxis. Eur J Dermatol (EJD). 1999;9(5):390–2.

    CAS  Google Scholar 

  36. Walling HW. Subclinical onychomycosis is associated with tinea pedis. Br J Dermatol. 2009;161(4):746–9.

    Article  CAS  PubMed  Google Scholar 

  37. Staberg B, Gammeltoft M, Onsberg P. Onychomycosis in patients with psoriasis. Acta Derm Venereol. 1983;63(5):436–8.

    CAS  PubMed  Google Scholar 

  38. Gupta AK, Lynde CW, Jain HC, et al. A higher prevalence of onychomycosis in psoriatics compared with non-psoriatics: a multicentre study. Br J Dermatol. 1997;136(5):786–9.

    Article  CAS  PubMed  Google Scholar 

  39. Larsen GK, Haedersdal M, Svejgaard EL. The prevalence of onychomycosis in patients with psoriasis and other skin diseases. Acta Derm Venereol. 2003;83(3):206–9.

    Article  PubMed  Google Scholar 

  40. Gupta AK, Gupta MA, Summerbell RC, et al. The epidemiology of onychomycosis: possible role of smoking and peripheral arterial disease. J Eur Acad Dermatol Venereol (JEADV). 2000;14(6):466–9.

    Article  CAS  Google Scholar 

  41. Ozkan F, Ozturk P, Ozyurt K, et al. Frequency of peripheral arterial disease and venous insufficiency in toenail onychomycosis. J Dermatol. 2013;40(2):107–10.

    Article  PubMed  Google Scholar 

  42. Saez de Ocariz MM, Arenas R, Ranero-Juarez GA, Farrera-Esponda F, Monroy-Ramos E. Frequency of toenail onychomycosis in patients with cutaneous manifestations of chronic venous insufficiency. Int J Dermatol. 2001;40(1):18–25.

    Article  CAS  PubMed  Google Scholar 

  43. Fukunaga A, Washio K, Ogura K, et al. Onychomycosis as a warning sign for peripheral arterial disease. Acta Derm Venereol. 2013;93(6):747–8.

    Article  PubMed  Google Scholar 

  44. Eisele SA. Conditions of the toenails. Orthop Clin North Am. 1994;25(1):183–8.

    CAS  PubMed  Google Scholar 

  45. Gudnadottir G, Hilmarsdottir I, Sigurgeirsson B. Onychomycosis in Icelandic swimmers. Acta Derm Venereol. 1999;79(5):376–7.

    Article  CAS  PubMed  Google Scholar 

  46. Nurhan Doner SY. Tugba Rezan Emekci Evaluation of Obesity-Associated Dermatoses in Obese and Overweight Individuals. Turkderm. 2011;45(3):146–51.

    Article  Google Scholar 

  47. Bandh SA, Kamili AN, Ganai BA, Lone BA. Opportunistic fungi in lake water and fungal infections in associated human population in Dal Lake, Kashmir. Microb Pathog. 2016;93:105–10.

    Article  PubMed  Google Scholar 

  48. Tosti A, Piraccini BM, Lorenzi S. Onychomycosis caused by nondermatophytic molds: clinical features and response to treatment of 59 cases. J Am Acad Dermatol. 2000;42(2 Pt 1):217–24.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Antonella Tosti MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Jacobsen, A.A., Tosti, A. (2017). Predisposing Factors for Onychomycosis. In: Tosti, A., Vlahovic, T., Arenas, R. (eds) Onychomycosis. Springer, Cham. https://doi.org/10.1007/978-3-319-44853-4_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-44853-4_2

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44852-7

  • Online ISBN: 978-3-319-44853-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics