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Ligament Tissue Engineering

  • Wasim KhanEmail author
Chapter
Part of the Studies in Mechanobiology, Tissue Engineering and Biomaterials book series (SMTEB, volume 21)

Abstract

Ligaments are commonly injured in the knee joint, and have a poor capacity for healing due to their relative avascularity. Ligament reconstruction is well established for injuries such as anterior cruciate ligament rupture, however the use of autografts and allografts for ligament reconstruction are associated with complications, and outcomes are variable. Ligament tissue engineering using stem cells, growth factors and scaffolds is a novel technique that has the potential to provide an unlimited source of tissue. In this chapter we discuss the role of tissue engineering in dealing with ligament injuries and provide an overview of in vitro and in vivo studies.

Keywords

Anterior Cruciate Ligament Anterior Cruciate Ligament Reconstruction Platelet Derive Growth Factor Anterior Cruciate Ligament Injury Medial Collateral Ligament 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic HospitalUniversity College LondonStanmoreUK

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