• Nicola FerraraEmail author
  • Graziamaria Corbi
  • Klara Komici
  • Giuseppe Rengo


Polypharmacy has been defined by the World Health Organization as “the administration of many drugs at the same time or the administration of an excessive number of drugs” [1]. Even if the use of more drugs in many cases has been justified by concomitant diseases and complex medical situations, it is not rare, especially in old patients, the prescription of more inappropriate drugs increasing the risk of iatrogenesis defined as adverse health effects caused by medical practices or drugs prescribed by doctors for the health of the patients at the usual way or doses.


Inappropriate Prescription Inappropriate Drug Relevant Drug Interaction High Symptom Score Pulmonary Adverse Event 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Nicola Ferrara
    • 1
    • 2
    Email author
  • Graziamaria Corbi
    • 3
  • Klara Komici
    • 1
  • Giuseppe Rengo
    • 1
    • 2
  1. 1.Department of Translational Medical SciencesUniversity of Naples “Federico II”NapoliItaly
  2. 2.S. Maugeri FoundationScientific Institute of Telese Terme (BN), IRCCSTelese TermeItaly
  3. 3.Department of Medicine and Health SciencesUniversity of MoliseCampobassoItaly

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