Do Different Populations of Rectal Cancer Exist?

  • Vincenzo Valentini
  • Francesco Cellini
  • Maria Cristina Barba
  • Ruud van Stiphout


The impact of new treatments for rectal cancer has substantially improved patients’ clinical outcomes in the last few years, but still worldwide colorectal cancer remains the third most common. In 2000, colorectal cancer was responsible for 7.9% of the world’s cancer deaths, with 492,000 deaths; it accounted for 9.4% of the world’s new cancers registered, with 945,000 cases diagnosed (Parkin Lancet Oncol 2(9):533–543, 2001; National Cancer Institute: PDQ® Rectal Cancer Treatment. National Cancer Institute, Bethesda (2011)


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Copyright information

© Springer-Verlag Berlin Heidelberg 2018

Authors and Affiliations

  • Vincenzo Valentini
    • 1
    • 2
  • Francesco Cellini
    • 3
  • Maria Cristina Barba
    • 1
    • 2
  • Ruud van Stiphout
    • 4
  1. 1.Department of RadiotherapyUniversità Cattolica Sacro CuoreRomeItaly
  2. 2.Policlinico Universitario ‘A. Gemelli’RomeItaly
  3. 3.Radioterapia OncologicaUniversità Campus BiomedicoRomeItaly
  4. 4.Department of Radiation Oncology (MAASTRO)GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre+MaastrichtThe Netherlands

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