Abstract
Challenges for the control of scabies in Oceania include the requirement for combining public health and biomedical strategies. There is a critical need for more baseline epidemiological information, and sustained improvements will not occur without addressing the primordial development issues of housing, sanitation, hygiene, nutrition, education, and maternal health. Recent studies from Fiji provide optimism for the future, including a large mass drug administration program showing oral ivermectin to have superior effectiveness in comparison to topical permethrin. This will help form the basis of a more coordinated approach to scabies as a neglected tropical disease with global visibility. Lessons from development of control programs for other neglected tropical diseases will also help optimize both scabies-specific strategies and their coordination with and integration into existing clinical and public health programs. The importance of scabies as a driver of high rates of bacterial skin infections and their sequelae is well recognized. Ongoing applied biomedical research is directed at better understanding the immunological responses to scabies infection, development of better and more specific diagnostics including direct mite detection and serological assays, vaccine development, and understanding the complex immunopathogenetic interactions between scabies mites and skin bacteria such as streptococci and staphylococci.
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Walton, S.F., Currie, B.J. (2016). Scabies. In: Loukas, A. (eds) Neglected Tropical Diseases - Oceania. Neglected Tropical Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-43148-2_10
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