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POPs and Skin

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Environment and Skin

Abstract

Persistent organic pollutants (POPs) is the name of a group of ubiquitous man-made toxic environmental pollutants which have adverse effects on the environment and human health. The skin is a major target organ of toxic effects of POPs as well as signalling organ for the toxicity of these compounds. Chloracne is the most obvious signs of systemic contact with higher levels of POPs with chloracnegenic potential. First we will discuss chemical and toxicological properties of POPs and finally the pathophysiology of cutaneous diseases derived from POPs including acne, cancerogenesis, porphyria and others.

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Authors and Affiliations

  1. Department of Dermatology and Allergology, RWTH Aachen University, Pauwelstrasse 30, Aachen, 52075, Germany

    M. M. Leijs, J. M. Baron & H. F. Merk

  2. Department of Paediatrics and Pulmonology, Emma Children’s Hospital, Academic Medical Center, Meibergdreef 9, Amsterdam, 1105, AZ, The Netherlands

    Janna G. Koppe

  3. Ecobaby Foundation, Hollandstraat 6, Loenersloot, 3634 AT, The Netherlands

    Janna G. Koppe

  4. Institute of Occupational Medicine, RWTH Aachen University, Pauwelstrasse 30, Aachen, 52074, Germany

    T. Kraus

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  1. M. M. Leijs
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  2. Janna G. Koppe
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  3. T. Kraus
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  4. J. M. Baron
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  5. H. F. Merk
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Correspondence to M. M. Leijs .

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  1. IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany

    Jean Krutmann

  2. Universitätsklinikum Aachen Klinik für Dermatologie u. Allergologie, Aachen, Germany

    Hans F. Merk

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Leijs, M.M., Koppe, J.G., Kraus, T., Baron, J.M., Merk, H.F. (2018). POPs and Skin. In: Krutmann, J., Merk, H. (eds) Environment and Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-43102-4_10

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  • DOI: https://doi.org/10.1007/978-3-319-43102-4_10

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