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In Vitro Maturation of Human Oocytes

  • Zhi-Yong Yang
  • Ling Wang
  • Ri-Cheng Chian
Chapter

Abstract

There is a growing interest in natural cycle in vitro fertilization (IVF) and in vitro maturation (IVM) treatment. Recovery of immature oocytes followed by IVM is a potentially useful treatment for women with infertility. The method is particularly effective for infertile women who have numerous antral follicles due to polycystic ovaries or polycystic ovarian syndrome. Today, given the efficiency of IVF and improvements in the culture system, natural cycle IVF and mild stimulation IVF may be more suitable for women undergoing infertility treatment. One very attractive possibility for enhancing the successful outcome of natural cycle or mild stimulation IVF treatment is combining it with immature egg retrieval and IVM. The use of IVM technology can thus be broadened to treat women suffering from all causes of infertility. In the meantime, it opens a possibility for cancer patients for fertility preservation, because some cancer patients cannot be treated with ovarian stimulation. The aim of this chapter is to share our experience and protocols with the assisted reproductive technology (ART) fraternity.

Keywords

Immature oocytes IVM Fertilization Pregnancy Natural cycle Mild stimulation 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Zhi-Yong Yang
    • 1
  • Ling Wang
    • 1
  • Ri-Cheng Chian
    • 1
  1. 1.Center for Reproductive MedicineShanghai 10th People’s Hospital of Tongji UniversityShanghaiChina

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