Abstract
In the era of Internet, high connectivity and openness introduced an opportunity for a new kind of approach to healthcare information system integration. Such an approach may utilize semantic-based technologies to represent and communicate knowledge between these systems. Resource Description Framework (RDF) in conjunction with Web Ontology Language (OWL) can be considered as a de facto standard when it comes to semantic web and linked data technologies, and represents a foundation for defining healthcare ontologies. The goal of this paper is to provide an overview and critical review of existing healthcare ontologies and approaches to healthcare IS integration, focusing on OWL/RDF based solutions. With this review we want to show that although a lot work is done in this area, no universal or omnipresent solution has surfaced to allow automatic or at least semi-automatic integration of healthcare ISs. As there is a large number of established and emerging ontologies covering this subject our review will not provide an exhaustive collection of all the references in the area, but present the most notable standards, ontologies, taxonomies, and integration approaches.
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Ontology Alignment Evaluation Initiative - http://oaei.ontologymatching.org/.
References
Beale, T.: Archetypes: constraint-based domain models for future-proof information systems. In: Workshop on Behavioural Semantics, OOPSLA, vol. 105, Seattle, USA, November 2002 (2002)
Beredimas, N., Kilintzis, V., Chouvarda, I., Maglaveras, N.: A reusable ontology for primitive and complex HL7 FHIR data types. In: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), August 2015, pp. 2547–2550. IEEE (2005)
Bicer, V., Laleci, G.B., Dogac, A., Kabak, Y.: Artemis message exchange framework: semantic interoperability of exchanged messages in the healthcare domain. ACM Sigmod Rec. 34(3), 71–76 (2005)
Bodenreider, O.: The unified medical language system (UMLS): integrating biomedical terminology. Nucleic Acids Res. 32(1), 267–270 (2004)
David Booth, C., Huff, S.M., Fry, E., Dowling, C., Mandel, J.C.: RDF as a Universal Healthcare Exchange Language (2013)
Cardillo, E.: Mapping between international medical terminologies, May 2015
Coyle, J., Heras, Y., Oniki, T., Huff, S.: Clinical element model. Technical report, University of Utah (2008)
Feng, L., Li, Y., Liu, L., Ye, X., Wang, J., Cao, Z., Peng, X.: Towards an applied oral health ontology: a round trip between clinical data and experiential medical knowledge. In: Proceedings of 39th Annual Computer Software and Applications Conference (COMPSAC), vol. 3, pp. 288–295, July 2015. IEEE (2015)
Olaronke, I., Soriyan, H., Abimbola, G.P., Gambo, I.: Resolving semantic heterogeneity in healthcare: an ontology matching approach. J. Comput. Sci. Eng. 17(2) (2013)
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res. 32(1), 258–261 (2004)
Chen, H.: HL7 RIM V3 OWL Ontology for Semantic Web
Heymans, S., McKennirey, M., Phillips, J.: Semantic validation of the use of SNOMED CT in HL7 clinical documents. J. Biomed. Semant. 2(1), 2 (2011)
Hoffmann, A., Kang, B.-H., Richards, D., Tsumoto, S. (eds.): PKAW 2006. LNCS (LNAI), vol. 4303. Springer, Heidelberg (2006)
Iqbal, A.M.: An OWL-DL ontology for the HL7 reference information model. In: Abdulrazak, B., Giroux, S., Bouchard, B., Pigot, H., Mokhtari, M. (eds.) ICOST 2011. LNCS, vol. 6719, pp. 168–175. Springer, Heidelberg (2011)
James, A.: Qualibria Constraint Definition Language (CDL). Technical report (2010)
Fernández-Breis, J.T., Vivancos-Vicente, P.J., Menárguez-Tortosa, M., Moner, D., Maldonado, J.A., Valencia-García, R., Miranda-Mena, T.G.: Using semantic technologies to promote interoperability between electronic healthcare records’ information models. In: Proceedings of the 28th IEEE EMBS Annual International Conference, New York City, USA, pp. 2614–2617. IEEE (2006)
Khan, W.A., Khattak, A.M., Lee, S., Hussain, M., Amin, B., Latif, K.: Achieving interoperability among healthcare standards: building semantic mappings at models level. In: Proceedings of the 6th International Conference on Ubiquitous Information Management and Communication, New York, USA, p. 101. ACM (2012)
Lipscomb, C.E.: Lipscomb: Medical Subject Headings (MeSH). Bull. Med. Libr. Assoc. 88(3), 265–266 (2000)
Liu, S., Ni, Y., Mei, J., Li, H., Xie, G., Hu, G., Liu, H., Hou, X., Pan, Y.: iSMART: ontology-based semantic query of CDA documents. AMIA Annu. Symp. Proc. 2009, 375–379 (2009)
Liu, S., Ma, W., Moore, R., Ganesan, V., Nelson, S.: RxNorm: prescription for electronic drug information exchange. IT Prof. 7(5), 17–23 (2005)
Luz, M.P., Rocha de Matos Nogueira, J., Cavalini, L.T., Cook, T.W.: Providing full semantic interoperability for the fast healthcare interoperability resources schemas with resource description framework. In: Proceedings of 2015 International Conference on Healthcare Informatics (ICHI), Dallas, TX, October 2015, pp. 463–466. IEEE (2015)
Martínez-Costa, C., Menárguez-Tortosa, M., Fernández-Breis, J.T.: An approach for the semantic interoperability of ISO EN 13606 and OpenEHR archetypes. J. Biomed. Inform. 43(5), 736–746 (2010)
McDonald, C.J., Huff, S.M., Suico, J.G., Hills, G., Leavelle, D., Aller, R., Forrey, A., Mercer, K., DeMoor, G., Hook, J., et al.: LOINC, a universal standard for identifying laboratory observations: a 5-year update. Chem. Clin. 49(4), 624–633 (2003)
Menárguez-Tortosa, M., Fernández-Breis, J.T.: Semantic interoperability for better health and safer healthcare: research and deployment roadmap for Europe. Semantic health report January 2009. In: Proceedings of User Centred Networked Health Care, Luxembourg. EUR-OP (2009)
Menárguez-Tortosa, M., Fernández-Breis, J.T.: OWL-based reasoning methods for validating archetypes. J. Biomedical Inf. 46(2), 304–317 (2013)
Nejhadi, A.H., Shadgar, B., Osareh, A.: Ontology alignment using machine learning techniques. Int. J. Comput. Sci. Inf. Technol. 3(2), 139–150 (2011)
Oemig, F., Blobel, B.: An ontology architecture for HL7 V3: pitfalls and outcomes. In: Dössel, O., Schlegel, W.C. (eds.) IFMBE Proceedings of the World Congress on Medical Physics and Biomedical Engineering, vol. 12, pp. 408–410. Springer, Heidelberg (2009)
Orgun, B., Vu, J.: HL7 ontology and mobile agents for interoperability in heterogeneous medical information systems. Comput. Biol. Med. 36(7–8), 817–836 (2006)
Puri, C.A., Gomadam, K., Jain, P., Yeh, P.Z., Verma, K.: Multiple ontologies in healthcare information technology: motivations and recommendation for ontology mapping and alignment. In: International Conference on Biomedical Ontologies (ICBO) (2011)
Santos, M.R., Bax, M.P., Kalra, D.: Building a logical EHR architecture based on ISO 13606 standard and semantic web technologies. Stud. Health Technol. Inf. 160(1), 161–165 (2010)
Schadow, G., Mead, C.N., Walker, D.M.: The HL7 reference information model under scrutiny. Stud. Health Technol. Inf. 124, 151–156 (2006)
Schloeffel, P., Beale, T., Hayworth, G., Heard, S., Leslie, H.: The relationship between CEN 13606, HL7, and OpenEHR. In: Proceedings of HIC 2006 and HINZ 2006, pp. 24–28 (2006)
Schriml, L.M., Arze, C., Nadendla, S., Chang, Y.-W., Mazaitis, M., Felix, V., Feng, G., Kibbe, W.A.: Disease ontology: a backbone for disease semantic integration. Nucleic Acids Res. 40(1), 940–946 (2012)
Smith, B., Ashburner, M., Rosse, C., Bard, J., Bug, W., Ceusters, W., Goldberg, L.J., Eilbeck, K., Ireland, A., Mungall, C.J., Leontis, N., Rocca-Serra, P., Ruttenberg, A., Sansone, S.-A., Scheuermann, R.H., Shah, N., Whetzel, P.L., Lewis, S.: The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nat. Biotechnol. 25(11), 1251–1255 (2007)
Smith, B., Ceusters, W.: HL7 RIM: an incoherent standard. Stud. Health Technol. Inf. 124, 133–138 (2006)
Sunitha, A., Babu, G.S.: Ontology-driven knowledge-based health-care system, an emerging area - challenges and opportunities - Indian Scenario. ISPRS - Int. Arch. Photogrammetry Remote Sens. Spatial Inf. Sci. XL–8, 239–246 (2014)
Tao, C., Jiang, G., Oniki, T.A., Freimuth, R.R., Zhu, Q., Sharma, D., Pathak, J., Huff, S.M., Chute, C.G.: A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data. J. Am. Med. Inf. Assoc. 20(3), 554–562 (2013)
Vizenor, L.: Actions in health care organizations: an ontological analysis. Stud. Health Technol. Inf. 2(107), 1403–1407 (2004)
Vizenor, L., Smith, B., Ceusters, W.: Foundation for the Electronic Health Record: An Ontological Analysis of the HL7’s Reference Information Model (2004)
World Health Organization: International Statistical Classification of Diseases and Related Health Problems. World Health Organization (2004)
Acknowledgments
This research is supported by the Ministry of Education, Science, and Technological Development of Republic of Serbia, Grant III–47003: “Infrastructure for technology enhanced learning in Serbia” and Grant III–44010: “Intelligent Systems for Software Product Development and Business Support based on Models.”.
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Dimitrieski, V., Petrović, G., Kovačević, A., Luković, I., Fujita, H. (2016). A Survey on Ontologies and Ontology Alignment Approaches in Healthcare. In: Fujita, H., Ali, M., Selamat, A., Sasaki, J., Kurematsu, M. (eds) Trends in Applied Knowledge-Based Systems and Data Science. IEA/AIE 2016. Lecture Notes in Computer Science(), vol 9799. Springer, Cham. https://doi.org/10.1007/978-3-319-42007-3_32
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