Skip to main content
Book cover

International Workshop on Breast Imaging

IWDM 2016: Breast Imaging pp 122–129Cite as

Simulation of Positron Emission Mammography Imaging with Pixelated CdTe.

Part of the Lecture Notes in Computer Science book series (LNIP,volume 9699)

Abstract

The Voxel Imaging PET (VIP) Pathfinder project presents a new approach for the design of nuclear medicine imaging diagnostic devices by using highly segmented pixel CdTe sensors. State-of-the-art PET devices are made from scintillator crystals which have an energy resolution of about 10 %. Because of their limited energy resolution, the scatter fraction is relatively large. Their limited spatial resolution will introduce a parallax error and deficiency in the depth of interaction (DOI) determination (> 5 mm FWHM) and therefore a wrong line of response (LOR). In this study, we present a design for a breast dedicated PET based on CdTe detectors which have an energy resolution of about 1 % and can be easily segmented into small voxels for optimal spatial resolution to provide a solution for these setbacks. This simulation study will assess the advantages of this design for breast imaging purposes.

Keywords

  • Unit Module
  • Scatter Fraction
  • Positron Emission Mammograph
  • Parallax Error
  • Coincidence Window

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-3-319-41546-8_16
  • Chapter length: 8 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   84.99
Price excludes VAT (USA)
  • ISBN: 978-3-319-41546-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD   109.99
Price excludes VAT (USA)
Learn about institutional subscriptions
Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Fig. 7.

Notes

  1. 1.

    Note that this only affects the triggering pixel. All other pixels in the detector are still ready to measure new events.

  2. 2.

    Note that the NEMA NU 4-2008 standard to measure the SF is different from the previously described standard to measure sensitivity.

References

  1. Hruska, C.B., O’Connor, M.K.: Nuclear imaging of the breast: translating achievements in instrumentation into clinical use. Med Phys. 40(5), 050901 (2013)

    CrossRef  Google Scholar 

  2. Luo, W., et al.: Performance evaluation of a PEM scanner using the NEMA NU 4–2008 small animal PET standards. IEEE Trans. Nucl. Sci. 57, 94–103 (2010)

    CrossRef  Google Scholar 

  3. MacDonald, L., et al.: Clinical imaging characteristics of the positron emission mammography camera: PEM Flex Solo II. J. Nucl. Med. 50, 1666–1675 (2009)

    CrossRef  Google Scholar 

  4. Lerche, C.W., et al.: Dependency of energy-, position- and depth of interaction resolution on scintillation crystal coating and geometry. IEEE Trans. Nucl. Sci. 55, 1344–1351 (2008)

    CrossRef  Google Scholar 

  5. Mikhaylova, E., et al.: Simulation of the expected performance of a seamless scanner for brain PET based on highly pixelated CdTe Detectors. IEEE Trans. Med. Imaging 33, 332–339 (2014)

    CrossRef  Google Scholar 

  6. Ariño, G., et al.: Characterization of CdTe detector for use in PET. In: IEEE Conference Record on NSS & MIC, pp. 4598–4603 (2011)

    Google Scholar 

  7. De Lorenzo, G., et al.: Pixelated CdTe detectors to overcome intrinsic limitations of crystal based positron emission mammographs. J. Instrum. 8, C01030 (2013)

    Google Scholar 

  8. Calderón, Y.: Design, Development, and Modeling of a Compton Camera Tomographer Based on Room Temperature Solid State Pixel Detector. Ph.D. Thesis, Universitat Autònoma de Barcelona (UAB) (2014)

    Google Scholar 

  9. Arce, P., et al.: Gamos: a framework to do Geant4 simulations in different physics fields with an user-friendly interface. Nucl. Instr. Meth. Phys. Res. A 735, 304–313 (2014)

    CrossRef  Google Scholar 

  10. Ariño, G., et al.: Energy and coincidence time resolution measurements of CdTe detectors for PET. J. Instrum. 8, C02015 (2013)

    CrossRef  Google Scholar 

  11. Kolstein, M., et al.: Evaluation of list-mode ordered subset expectation maximization image reconstruction for pixelated solid-state compton gamma camera with large number of channels. J. Instrum. 9, C04034 (2014)

    CrossRef  Google Scholar 

  12. NEMA standards publication NU 4–2008: Performance measurements for small animal positron emission tomographs. National Electrical Manufacturers Association, Rosslyn, VA (2008)

    Google Scholar 

  13. Furuta, M., et al.: Basic evaluation of a C-shaped breast PET scanner. In: IEEE NSS & MIC Conference Record, pp. 2548–2552. IEEE (2009)

    Google Scholar 

  14. Ferreira, C.S., et al.: Scatter and attenuation corrections for a PEM detector using list-mode OSEM. In: IEEE Conference Record on NSS & MIC, pp. 1–4 (2013)

    Google Scholar 

Download references

Acknowledgements

This work has received funding from the European Research Council under the European Union’s Seventh Framework Programme (ERC Grant Agreement 250207, “VIP”). We also acknowledge the support from the Spanish MINECO under the Severo Ochoa excellence program (grant SO-2012-0234).

Author information

Authors and Affiliations

  1. Institut de Física D’Altes Energies (IFAE), The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain

    Machiel Kolstein & Mokhtar Chmeissani

Authors
  1. Machiel Kolstein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mokhtar Chmeissani
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Machiel Kolstein .

Editor information

Editors and Affiliations

  1. Lund Univ. and Skåne University Hospital, Sweden

    Anders Tingberg

  2. Lund Univ. and Unilabs, Malmö, Sweden

    Kristina Lång

  3. Lund Univ. and Skåne University Hospital, Malmö, Sweden

    Pontus Timberg

Rights and permissions

Reprints and Permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this paper

Cite this paper

Kolstein, M., Chmeissani, M. (2016). Simulation of Positron Emission Mammography Imaging with Pixelated CdTe. . In: Tingberg, A., Lång, K., Timberg, P. (eds) Breast Imaging. IWDM 2016. Lecture Notes in Computer Science(), vol 9699. Springer, Cham. https://doi.org/10.1007/978-3-319-41546-8_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-41546-8_16

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-41545-1

  • Online ISBN: 978-3-319-41546-8

  • eBook Packages: Computer ScienceComputer Science (R0)