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Adhesion G Protein-coupled Receptors pp 43–66Cite as

7TM Domain Structure of Adhesion GPCRs

Part of the Handbook of Experimental Pharmacology book series (HEP,volume 234)

Keywords

  • GPCR sequence alignment
  • Adhesion GPCR residue nomenclature
  • Adhesion GPCR sequence-structure relationship
  • Druggability adhesion GPCRs

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Acknowledgements

This work was supported by the Netherlands Organization for Scientific Research (NWO VENI grant 722.014.011 to SN), the Netherlands eScience Center (NLeSC)/NWO (Enabling Technologies project, 3D-e-Chem, grant 027.014.201 to CdG), the National Natural Science Foundation of China (NSFC, Research Fund for International Young Scientists, grant No. 31250110070 to SW) and the Canada Excellence Research Chair program (OPE). OPE holds the Anne and Max Tanenbaum Chair in Neuroscience at the University of Toronto. SN and CdG participate in the European Cooperation in Science and Technology Action CM1207 [GPCR-Ligand Interactions, Structures, and Transmembrane Signalling: A European Research Network (GLISTEN)] and the GPCR Consortium (gpcrconsortium.org).

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  1. Steffen Wolf

    Present address: Institute of Physics, Albert Ludwigs University, Freiburg, Germany

Authors and Affiliations

  1. Department of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, Amsterdam, 1081HV, The Netherlands

    Saskia Nijmeijer & Chris de Graaf

  2. Department of Biophysics, CAS-MPG Partner Institute for Computational Biology, Key Laboratory of Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P.R. China

    Steffen Wolf

  3. Department of Biochemistry, University of Toronto, 1 King’s College Circle, Toronto, ON, Canada, M5S 1A8

    Oliver P. Ernst

  4. Department of Molecular Genetics, University of Toronto, 1 King’s College Circle, Toronto, ON, Canada, M5S 1A8

    Oliver P. Ernst

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  1. Saskia Nijmeijer
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  2. Steffen Wolf
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  3. Oliver P. Ernst
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  4. Chris de Graaf
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Correspondence to Chris de Graaf .

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Editors and Affiliations

  1. Institute of Physiology Department of Neurophysiology, University of Würzburg, Würzburg, Germany

    Tobias Langenhan

  2. Institute of Biochemistry Medical Faculty, University of Leipzig, Leipzig, Germany

    Torsten Schöneberg

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Nijmeijer, S., Wolf, S., Ernst, O.P., de Graaf, C. (2016). 7TM Domain Structure of Adhesion GPCRs. In: Langenhan, T., Schöneberg, T. (eds) Adhesion G Protein-coupled Receptors. Handbook of Experimental Pharmacology, vol 234. Springer, Cham. https://doi.org/10.1007/978-3-319-41523-9_3

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