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Anovulatory Disorders

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Managing Ultrasonography in Human Reproduction

Abstract

Anovulation is one of the main causes of infertility affecting about 30 % of women with infertility [1]. The World Health Organization (WHO) has classified anovulatory disorders into three categories [2, 3]:

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References

  1. Hamilton-Fairley D, Taylor A. Anovulation. BMJ. 2003;327:546–9.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Propst AM, Bates Jr GW. Evaluation and treatment of anovulatory and unexplained infertility. Obstet Gynecol Clin North Am. 2012;39:507–19.

    Article  PubMed  Google Scholar 

  3. ESHRE Capri Workshop Group. Health and fertility in World Health Organization group 2 anovulatory women. Hum Reprod Update. 2012;18:586–99.

    Article  Google Scholar 

  4. Yaman C, Jesacher K, Pölz W. Accuracy of three-dimensional transvaginal ultrasound in uterus volume measurements; comparison with two-dimensional ultrasound. Ultrasound Med Biol. 2003;29:1681–4.

    Article  PubMed  Google Scholar 

  5. Raine-Fenning NJ, Campbell BK, Clewes JS, Kendall NR, Johnson IR. The interobserver reliability of three-dimensional power Doppler data acquisition within the female pelvis. Ultrasound Obstet Gynecol. 2004;23:501–8.

    Article  CAS  PubMed  Google Scholar 

  6. Mercé LT, Garcés D, Barco MJ, de la Fuente F. Intraovarian Doppler velocimetry in ovulatory, dysovulatory and anovulatory cycles. Ultrasound Obstet Gynecol. 1992;2:197–202.

    Article  PubMed  Google Scholar 

  7. Sladkevicius P, Valentin L. Reproducibility of Doppler measurements of blood flow velocity in the uterine and ovarian arteries in premenopausal women. Ultrasound Med Biol. 1995;21:313–9.

    Article  CAS  PubMed  Google Scholar 

  8. Pairleitner H, Steiner H, Hasenoehrl G, Staudach A. Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. Ultrasound Obstet Gynecol. 1999;14:139–43.

    Article  CAS  PubMed  Google Scholar 

  9. Jones NW, Hutchinson ES, Brownbill P, Crocker IP, Eccles D, Bugg GJ, Raine-Fenning NJ. In vitro dual perfusion of human placental lobules as a flow phantom to investigate the relationship between fetoplacental flow and quantitative 3D power Doppler angiography. Placenta. 2009;30:130–5.

    Article  CAS  PubMed  Google Scholar 

  10. Raine-Fenning NJ, Nordin NM, Ramnarine KV, Campbell BK, Clewes JS, Perkins A, Johnson IR. Determining the relationship between three-dimensional power Doppler data and true blood flow characteristics: an in-vitro flow phantom experiment. Ultrasound Obstet Gynecol. 2008;32:540–50.

    Article  CAS  PubMed  Google Scholar 

  11. Mercé LT, Gómez B, Engels V, Bau S, Bajo JM. Intraobserver and interobserver reproducibility of ovarian volume, antral follicle count, and vascularity indices obtained with transvaginal 3-dimensional ultrasonography, power Doppler angiography, and the virtual organ computer-aided analysis imaging program. J Ultrasound Med. 2005;24:1279–87.

    PubMed  Google Scholar 

  12. Kudla MJ, Alcázar JL. Spatiotemporal image correlation with spherical sampling and high-definition flow: new 4-dimensional method for assessment of tissue vascularization changes during the cardiac cycle: reproducibility analysis. J Ultrasound Med. 2012;31:73–80.

    PubMed  Google Scholar 

  13. Alcázar JL, Kudla MJ. Ovarian stromal vessels assessed by spatiotemporal image correlation-high definition flow in women with polycystic ovary syndrome: a case-control study. Ultrasound Obstet Gynecol. 2012;40:470–5.

    Article  PubMed  Google Scholar 

  14. Alcazar JL, Zornoza A. Transvaginal ultrasonographic measurement of endometrial thickness: an intra-observer and interobserver reproducibility study. Radiography. 2001;7:101–4.

    Article  Google Scholar 

  15. Martins WP, Ferriani RA, Barra DA, Dos Reis RM, Bortolieiro MA, Nastri CO, Filho FM. Reliability and validity of tissue volume measurement by three-dimensional ultrasound: an experimental model. Ultrasound Obstet Gynecol. 2007;29:210–4.

    Article  CAS  PubMed  Google Scholar 

  16. Alcázar JL, Mercé LT, Manero MG, Bau S, López-García G. Endometrial volume and vascularity measurements by transvaginal 3-dimensional ultrasonography and power Doppler angiography in stimulated and tumoral endometria: an interobserver reproducibility study. J Ultrasound Med. 2005;2:1091–8.

    Google Scholar 

  17. Huey S, Abuhamad A, Barroso G, Hsu MI, Kolm P, Mayer J, Oehninger S. Perifollicular blood flow Doppler indices, but not follicular pO2, pCO2, or pH, predict oocyte developmental competence in in vitro fertilization. Fertil Steril. 1999;72:707–12.

    Article  CAS  PubMed  Google Scholar 

  18. Lai KY, de Bruyn R, Lask B, Bryant-Waugh R, Hankins M. Use of pelvic ultrasound to monitor ovarian and uterine maturity in childhood onset anorexia nervosa. Arch Dis Child. 1994;71:228–31.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Mason HD, Key A, Allan R, Lask B. Pelvic ultrasonography in anorexia nervosa: what the clinician should ask the radiologist and how to use the information provided. Eur Eat Disord Rev. 2007;15:35–41.

    Article  PubMed  Google Scholar 

  20. Balen AH, Laven JS, Tan SL, Dewailly D. Ultrasound assessment of the polycystic ovary: international consensus definitions. Hum Reprod Update. 2003;9:505–14.

    Article  PubMed  Google Scholar 

  21. Dewailly D, Gronier H, Poncelet E, Robin G, Leroy M, Pigny P, Duhamel A, Catteau-Jonard S. Diagnosis of polycystic ovary syndrome (PCOS): revisiting the threshold values of follicle count on ultrasound and of the serum AMH level for the definition of polycystic ovaries. Hum Reprod. 2011;26:3123–9.

    Article  CAS  PubMed  Google Scholar 

  22. Lujan ME, Jarrett BY, Brooks ED, Reines JK, Peppin AK, Muhn N, Haider E, Pierson RA, Chizen DR. Updated ultrasound criteria for polycystic ovary syndrome: reliable thresholds for elevated follicle population and ovarian volume. Hum Reprod. 2013;28:1361–8.

    Article  PubMed  Google Scholar 

  23. Martins WP, Kollmann M, Raine-Fenning N. Counting ovarian follicles: updated threshold for diagnosis of hyperandrogenic anovulation. Ultrasound Obstet Gynecol. 2014;44:131–4.

    Article  CAS  PubMed  Google Scholar 

  24. Dewailly D, Lujan ME, Carmina E, Cedars MI, Laven J, Norman RJ, Escobar-Morreale HF. Definition and significance of polycystic ovarian morphology: a task force report from the Androgen Excess and Polycystic Ovary Syndrome Society. Hum Reprod Update. 2014;20:334–52.

    Article  CAS  PubMed  Google Scholar 

  25. Fulghesu AM, Angioni S, Frau E, Belosi C, Apa R, Mioni R, Xamin N, Capobianco GP, Dessole S, Fruzzetti F, Lazzarini V, Minerba L, Melis GB, Lanzone A. Ultrasound in polycystic ovary syndrome--the measuring of ovarian stroma and relationship with circulating androgens: results of a multicentric study. Hum Reprod. 2007;22:2501–8.

    Article  CAS  PubMed  Google Scholar 

  26. Christ JP, Willis AD, Brooks ED, Vanden Brink H, Jarrett BY, Pierson RA, Chizen DR, Lujan ME. Follicle number, not assessments of the ovarian stroma, represents the best ultrasonographic marker of polycystic ovary syndrome. Fertil Steril. 2014;101:280–7.

    Article  PubMed  Google Scholar 

  27. Battaglia C, Artini PG, D’Ambrogio G, Genazzani AD, Genazzani AR. The role of color Doppler imaging in the diagnosis of polycystic ovary syndrome. Am J Obstet Gynecol. 1995;172:108–13.

    Article  CAS  PubMed  Google Scholar 

  28. Peri N, Levine D. Sonographic evaluation of the endometrium in patients with a history or an appearance of polycystic ovarian syndrome. J Ultrasound Med. 2007;26:55–8.

    PubMed  Google Scholar 

  29. Qublan H, Amarin Z, Nawasreh M, Diab F, Malkawi S, Al-Ahmad N, Balawneh M. Luteinized unruptured follicle syndrome: incidence and recurrence rate in infertile women with unexplained infertility undergoing intrauterine insemination. Hum Reprod. 2006;21:2110–3.

    Article  CAS  PubMed  Google Scholar 

  30. Tamura H, Takasaki A, Taniguchi K, Matsuoka A, Shimamura K, Sugino N. Changes in blood-flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy. Fertil Steril. 2008;90:2334–9.

    Article  PubMed  Google Scholar 

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Correspondence to Juan Luis Alcázar MD, PhD .

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Alcázar, J.L., Moya, M. (2017). Anovulatory Disorders. In: Guerriero, S., Martins, W., Alcazar, J. (eds) Managing Ultrasonography in Human Reproduction. Springer, Cham. https://doi.org/10.1007/978-3-319-41037-1_2

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  • DOI: https://doi.org/10.1007/978-3-319-41037-1_2

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  • Publisher Name: Springer, Cham

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