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Postmastectomy Radiotherapy with and Without Reconstruction

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Radiation Therapy Techniques and Treatment Planning for Breast Cancer

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

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Abstract

The role of radiotherapy after mastectomy, postmastectomy radiotherapy (PMRT), in women with node-positive or high-risk node-negative breast cancer has evolved over the last several decades since the publication of the randomized trials from the British Columbia Cancer Agency and the Danish Breast Cancer Cooperative Group [1–3]. These trials were the first trials using modern radiation techniques and systemic therapy to demonstrate that PMRT not only reduced locoregional recurrences (LRRs) but also improved survival. The impact of PMRT on local control and overall survival has been further supported by the results of the Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) meta-analysis [4, 5].

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA

    Kathleen C. Horst MD

  2. Department of Radiation Oncology, Stanford University, Stanford, CA, USA

    Nataliya Kovalchuk PhD & Carol Marquez MD

Authors
  1. Kathleen C. Horst MD
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  2. Nataliya Kovalchuk PhD
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  3. Carol Marquez MD
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Corresponding author

Correspondence to Kathleen C. Horst MD .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women’s Hospital Harvard Medical School, Boston, Massachusetts, USA

    Jennifer R. Bellon

  2. Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women’s Hospital Harvard Medical School, Boston, Massachusetts, USA

    Julia S. Wong

  3. Department of Radiation Oncology, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA

    Shannon M. MacDonald

  4. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Alice Y. Ho

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© 2016 Springer International Publishing Switzerland

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Horst, K.C., Kovalchuk, N., Marquez, C. (2016). Postmastectomy Radiotherapy with and Without Reconstruction. In: Bellon, J., Wong, J., MacDonald, S., Ho, A. (eds) Radiation Therapy Techniques and Treatment Planning for Breast Cancer. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-40392-2_2

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  • DOI: https://doi.org/10.1007/978-3-319-40392-2_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40390-8

  • Online ISBN: 978-3-319-40392-2

  • eBook Packages: MedicineMedicine (R0)

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