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Glucose Monitoring and Insulin Pump Therapy in the Management of Children and Adolescents with Type 1 Diabetes

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Research into Childhood-Onset Diabetes

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Abstract

Management of childhood and adolescent type 1 diabetes may be improved by combining insulin pump therapy with real-time glucose monitoring. We review recent technological advances in real-time glucose monitoring and pump therapy and assess impact on clinical efficacy, safety and psychosocial outcomes. Established clinical practice approaches such as sensor-augmented pump therapy and threshold suspend pump interruption are reviewed from paediatric perspective. Novel applications include predictive low glucose suspend to avoid impending hypoglycaemia.

The artificial pancreas (closed-loop systems) automates insulin delivery at low and high glucose levels and is the centre of the current research. We outline results of recent outpatient studies, limitations and conditions for a widespread use. We conclude that transformational progress has been made in the last decade promising iterative improvements in diabetes outcomes and quality of life through technological innovations of the artificial pancreas and its components.

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Authors and Affiliations

  1. Department of Paediatrics and Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK

    Martin Tauschmann & Roman Hovorka

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  1. Martin Tauschmann
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  2. Roman Hovorka
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Correspondence to Roman Hovorka .

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Editors and Affiliations

  1. Pediatric Diabetology Unit Department of Paediatrics, Luigi Sacco Hospital, Milan, Italy

    Andrea Scaramuzza

  2. Luxembourg Centre for Systems Biomedicin, Université du Luxembourg, Luxembourg, Luxembourg

    Carine de Beaufort

  3. Department of Paediatrics, Uddevalla Hospital, Uddevalla, Sweden

    Ragnar Hanas

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Tauschmann, M., Hovorka, R. (2017). Glucose Monitoring and Insulin Pump Therapy in the Management of Children and Adolescents with Type 1 Diabetes. In: Scaramuzza, A., de Beaufort, C., Hanas, R. (eds) Research into Childhood-Onset Diabetes. Springer, Cham. https://doi.org/10.1007/978-3-319-40242-0_14

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  • DOI: https://doi.org/10.1007/978-3-319-40242-0_14

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