Hematopoietic Stem Cell Transplantation and Cardiotoxicity

  • Annalisa Natale
  • Stella Santarone
  • Paolo Di Bartolomeo


Hematopoietic stem cell transplantation (HCT) is now used worldwide in the treatment of many malignant and non-malignant hematologic disorders and in the treatment of various solid tumors. Every year, many thousands of patients receive an autologous or allogeneic transplant procedure. Cardiac complications associated with HCT have been documented in several series, but the incidence of reported cardiotoxicity has varied largely among investigators, ranging from 2% to 28% probably reflecting patient selection, differences in HCT conditioning regimens and lack of universal grading system for cardiotoxic events.This chapter will focus on the cardiac complications occurring either in the early period following HCT or in the long-term phase.


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Annalisa Natale
    • 1
  • Stella Santarone
    • 1
  • Paolo Di Bartolomeo
    • 1
  1. 1.Dipartimento di Ematologia, Medicina Trasfusionale e Biotecnologie, Unità di Terapia Intensiva Ematologica per il Trapianto EmopoieticoOspedale CivilePescaraItaly

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