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Spinal Injuries of the Elderly

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Abstract

With this chapter, we aim to provide an up-to-date review of the relevant considerations for spinal neurosurgeons involved with the management of an elderly individual following traumatic injury to the spine. The first two sections focus on the features of traumatic injury and management considerations that differ between the elderly population and those in younger cohorts. The three subsequent sections deal with specific injuries common to the elderly, namely, odontoid fractures, traumatic central cord syndrome (TCCS), and vertebral compression fractures (VCRs). The final section concludes with a synopsis of the available evidence pertaining to the outcomes of elderly individuals. Common decision-making challenges will be highlighted, and areas of ongoing controversy are discussed. This should serve to raise awareness of certain pitfalls and facilitate appraisal of the continuing influx of new clinical data in this increasingly relevant and ever-changing area of spinal neurosurgery.

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References

  1. Krug EG, Dahlberg LL, Mercy JA, Zwi AB, Lozano R (2002) World report on violence and health. Lancet 360:1083–1088

    Article  PubMed  Google Scholar 

  2. Bengtson VL, Lowenstein A (2003) Global aging and its challenge to families. Transaction Publishers, New York

    Google Scholar 

  3. Devivo MJ (2012) Epidemiology of traumatic spinal cord injury: trends and future implications. Spinal Cord 50(5):365–372

    Article  CAS  PubMed  Google Scholar 

  4. Putzke JD, Barrett JJ, Richards JS, DeVivo MJ (2003) Age and spinal cord injury: an emphasis on outcomes among the elderly. J Spinal Cord Med 26(1):37–44

    Article  PubMed  Google Scholar 

  5. Lee BB, Cripps RA, Fitzharris M, Wing PC (2014) The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate. Spinal Cord 52(2):110–116

    Article  CAS  PubMed  Google Scholar 

  6. Elgafy H, Dvorak MF, Vaccaro AR, Ebraheim N (2009) Treatment of displaced type II odontoid fractures in elderly patients. Am J Orthop (Belle Mead NJ) 38(8):410–416

    Google Scholar 

  7. Malik SA, Murphy M, Connolly P, O’Byrne J (2008) Evaluation of morbidity, mortality and outcome following cervical spine injuries in elderly patients. Eur Spine J 17(4):585–591

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Lomoschitz FM, Blackmore CC, Mirza SK, Mann FA (2002) Cervical spine injuries in patients 65 years old and older: epidemiologic analysis regarding the effects of age and injury mechanism on distribution, type, and stability of injuries. AJR Am J Roentgenol 178(3):573–577

    Article  CAS  PubMed  Google Scholar 

  9. Ferguson SJ, Steffen T (2003) Biomechanics of the aging spine. Eur Spine J 12(Suppl 2):S97–S103

    Article  PubMed  PubMed Central  Google Scholar 

  10. Molinari RW, Khera OA, Gruhn WL, McAssey RW (2012) Rigid cervical collar treatment for geriatric type II odontoid fractures. Eur Spine J 21(5):855–862

    Article  PubMed  Google Scholar 

  11. Raudenbush B, Molinari R (2015) Longer-term outcomes of geriatric odontoid fracture nonunion. Geriatr Orthop Surg Rehabil 6(4):251–257

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lu C, Miclau T, Hu D et al (2005) Cellular basis for age-related changes in fracture repair. J Orthop Res 23(6):1300–1307

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Lu C, Hansen E, Sapozhnikova A, Hu D, Miclau T, Marcucio RS (2008) Effect of age on vascularization during fracture repair. J Orthop Res 26(10):1384–1389

    Article  PubMed  PubMed Central  Google Scholar 

  14. Terao S, Sobue G, Hashizume Y, Shimada N, Mitsuma T (1994) Age-related changes of the myelinated fibers in the human corticospinal tract: a quantitative analysis. Acta Neuropathol 88(2):137–142

    Article  CAS  PubMed  Google Scholar 

  15. Terao S, Sobue G, Hashizume Y, Li M, Inagaki T, Mitsuma T (1996) Age-related changes in human spinal ventral horn cells with special reference to the loss of small neurons in the intermediate zone: a quantitative analysis. Acta Neuropathol 92(2):109–114

    Article  CAS  PubMed  Google Scholar 

  16. Furlan JC, Bracken MB, Fehlings MG (2010) Is age a key determinant of mortality and neurological outcome after acute traumatic spinal cord injury? Neurobiol Aging 31(3):434–446

    Article  PubMed  Google Scholar 

  17. Committee on Trauma, American College of Surgeons (2012). ATLS: Advanced Trauma Life Support Program for Doctors (9th ed.). Chicago. American College of Surgeons

    Google Scholar 

  18. Milzman DP, Boulanger BR, Rodriguez A, Soderstrom CA, Mitchell KA, Magnant CM (1992) Pre-existing disease in trauma patients: a predictor of fate independent of age and injury severity score. J Trauma 32(2):236–243; discussion 243–234

    Article  CAS  PubMed  Google Scholar 

  19. Stevens RD, Bhardwaj A, Kirsch JR, Mirski MA (2003) Critical care and perioperative management in traumatic spinal cord injury. J Neurosurg Anesthesiol 15(3):215–229

    Article  PubMed  Google Scholar 

  20. Bonhomme V, Hans P (2009) Management of the unstable cervical spine: elective versus emergent cases. Curr Opin Anaesthesiol 22(5):579–585

    Article  PubMed  Google Scholar 

  21. Martyn JA, Richtsfeld M (2006) Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms. Anesthesiology 104(1):158–169

    Article  CAS  PubMed  Google Scholar 

  22. Aarabi B, Hadley MN, Dhall SS et al (2013) Management of acute traumatic central cord syndrome (ATCCS). Neurosurgery 72(Suppl 2):195–204

    Article  PubMed  Google Scholar 

  23. Bilello JF, Davis JW, Cunningham MA, Groom TF, Lemaster D, Sue LP (2003) Cervical spinal cord injury and the need for cardiovascular intervention. Arch Surg 138(10):1127–1129

    Article  PubMed  Google Scholar 

  24. Pasnoori VR, Leesar MA (2004) Use of aminophylline in the treatment of severe symptomatic bradycardia resistant to atropine. Cardiol Rev 12(2):65–68

    Article  PubMed  Google Scholar 

  25. Fehlings MG, Wilson JR, Cho N (2014) Methylprednisolone for the treatment of acute spinal cord injury: counterpoint. Neurosurgery 61(Suppl 1):36–42

    Article  PubMed  Google Scholar 

  26. Bracken MB, Shepard MJ, Holford TR et al (1997) Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. JAMA 277(20):1597–1604

    Article  CAS  PubMed  Google Scholar 

  27. Kayal RA, Tsatsas D, Bauer MA et al (2007) Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity. J Bone Miner Res 22(4):560–568

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Maier GS, Seeger JB, Horas K, Roth KE, Kurth AA, Maus U (2015) The prevalence of vitamin D deficiency in patients with vertebral fragility fractures. Bone Joint J 97-b(1):89–93

    Article  CAS  PubMed  Google Scholar 

  29. Einhorn TA, Bonnarens F, Burstein AH (1986) The contributions of dietary protein and mineral to the healing of experimental fractures. A biomechanical study. J Bone Joint Surg Am 68(9):1389–1395

    Article  CAS  PubMed  Google Scholar 

  30. Ryan MD, Henderson JJ (1992) The epidemiology of fractures and fracture-dislocations of the cervical spine. Injury 23(1):38–40

    Article  CAS  PubMed  Google Scholar 

  31. Hanigan WC, Powell FC, Elwood PW, Henderson JP (1993) Odontoid fractures in elderly patients. J Neurosurg 78(1):32–35

    Article  CAS  PubMed  Google Scholar 

  32. Muller EJ, Wick M, Russe O, Muhr G (1999) Management of odontoid fractures in the elderly. Eur Spine J 8(5):360–365

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Ryan MD, Taylor TK (1993) Odontoid fractures in the elderly. J Spinal Disord 6(5):397–401

    Article  CAS  PubMed  Google Scholar 

  34. Scheyerer MJ, Zimmermann SM, Simmen HP, Wanner GA, Werner CM (2013) Treatment modality in type II odontoid fractures defines the outcome in elderly patients. BMC Surg 13:54

    Article  PubMed  PubMed Central  Google Scholar 

  35. Anderson LD, D’Alonzo RT (1974) Fractures of the odontoid process of the axis. J Bone Joint Surg Am 56(8):1663–1674

    Article  CAS  PubMed  Google Scholar 

  36. Chiba K, Fujimura Y, Toyama Y, Fujii E, Nakanishi T, Hirabayashi K (1996) Treatment protocol for fractures of the odontoid process. J Spinal Disord 9(4):267–276

    Article  CAS  PubMed  Google Scholar 

  37. Ryken TC, Hadley MN, Aarabi B et al (2013) Management of isolated fractures of the axis in adults. Neurosurgery 72(Suppl 2):132–150

    Article  PubMed  Google Scholar 

  38. Chapman J, Smith JS, Kopjar B et al (2013) The AOSpine North America Geriatric Odontoid Fracture Mortality Study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up. Spine 38(13):1098–1104

    Article  PubMed  PubMed Central  Google Scholar 

  39. Smith JS, Kepler CK, Kopjar B et al (2013) Effect of type II odontoid fracture nonunion on outcome among elderly patients treated without surgery: based on the AOSpine North America geriatric odontoid fracture study. Spine (Phila Pa 1976) 38(26):2240–2246

    Google Scholar 

  40. Vaccaro AR, Kepler CK, Kopjar B et al (2013) Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture. J Bone Joint Surg Am 95(8):729–735

    Article  PubMed  Google Scholar 

  41. Schroeder GD, Kepler CK, Kurd MF et al (2015) A systematic review of the treatment of geriatric type II odontoid fractures. Neurosurgery 77(Suppl 4):S6–S14

    Article  PubMed  Google Scholar 

  42. Osti M, Philipp H, Meusburger B, Benedetto KP (2011) Analysis of failure following anterior screw fixation of Type II odontoid fractures in geriatric patients. Eur Spine J 20(11):1915–1920

    Article  PubMed  PubMed Central  Google Scholar 

  43. Nourbakhsh A, Shi R, Vannemreddy P, Nanda A (2009) Operative versus nonoperative management of acute odontoid Type II fractures: a meta-analysis. J Neurosurg Spine 11(6):651–658

    Article  PubMed  Google Scholar 

  44. Andersson S, Rodrigues M, Olerud C (2000) Odontoid fractures: high complication rate associated with anterior screw fixation in the elderly. Eur Spine J 9(1):56–59

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Majercik S, Tashjian RZ, Biffl WL, Harrington DT, Cioffi WG (2005) Halo vest immobilization in the elderly: a death sentence? J Trauma 59(2):350–356; discussion 356–358

    Article  PubMed  Google Scholar 

  46. Lennarson PJ, Mostafavi H, Traynelis VC, Walters BC (2000) Management of type II dens fractures: a case–control study. Spine (Phila Pa 1976) 25(10):1234–1237

    Article  CAS  Google Scholar 

  47. Joaquim AF, Patel AA (2015) Surgical treatment of Type II odontoid fractures: anterior odontoid screw fixation or posterior cervical instrumented fusion? Neurosurg Focus 38(4):E11

    Article  PubMed  Google Scholar 

  48. Koech F, Ackland HM, Varma DK, Williamson OD, Malham GM (2008) Nonoperative management of type II odontoid fractures in the elderly. Spine (Phila Pa 1976) 33(26):2881–2886

    Article  Google Scholar 

  49. Woods BI, Hohl JB, Braly B, Donaldson W 3rd, Kang J, Lee JY (2014) Mortality in elderly patients following operative and nonoperative management of odontoid fractures. J Spinal Disord Tech 27(6):321–326

    Article  PubMed  Google Scholar 

  50. Fehlings MG, Arun R, Vaccaro AR, Arnold PM, Chapman JR, Kopjar B (2013) Predictors of treatment outcomes in geriatric patients with odontoid fractures: AOSpine North America multi-centre prospective GOF study. Spine (Phila Pa 1976) 38(11):881–886

    Article  Google Scholar 

  51. Patel A, Smith HE, Radcliff K, Yadlapalli N, Vaccaro AR (2012) Odontoid fractures with neurologic deficit have higher mortality and morbidity. Clin Orthop Relat Res 470(6):1614–1620

    Article  PubMed  Google Scholar 

  52. Schneider RC, Cherry G, Pantek H (1954) The syndrome of acute central cervical spinal cord injury; with special reference to the mechanisms involved in hyperextension injuries of cervical spine. J Neurosurg 11(6):546–577

    Article  CAS  PubMed  Google Scholar 

  53. van Middendorp JJ, Hosman AJ, Pouw MH, Van de Meent H (2009) ASIA impairment scale conversion in traumatic SCI: is it related with the ability to walk? A descriptive comparison with functional ambulation outcome measures in 273 patients. Spinal Cord 47(7):555–560

    Article  PubMed  Google Scholar 

  54. Dahdaleh NS, Lawton CD, El Ahmadieh TY et al (2013) Evidence-based management of central cord syndrome. Neurosurg Focus 35(1):E6

    Article  PubMed  Google Scholar 

  55. Anderson KK, Tetreault L, Shamji MF et al (2015) Optimal timing of surgical decompression for acute traumatic central cord syndrome: a systematic review of the literature. Neurosurgery 77(Suppl 4):S15–S32

    Article  PubMed  Google Scholar 

  56. Bartels RH, Hosman AJ, van de Meent H et al (2013) Design of COSMIC: a randomized, multi-centre controlled trial comparing conservative or early surgical management of incomplete cervical cord syndrome without spinal instability. BMC Musculoskelet Disord 14:52

    Article  PubMed  PubMed Central  Google Scholar 

  57. Roth EJ, Lawler MH, Yarkony GM (1990) Traumatic central cord syndrome: clinical features and functional outcomes. Arch Phys Med Rehabil 71(1):18–23

    CAS  PubMed  Google Scholar 

  58. Penrod LE, Hegde SK, Ditunno JF Jr (1990) Age effect on prognosis for functional recovery in acute, traumatic central cord syndrome. Arch Phys Med Rehabil 71(12):963–968

    CAS  PubMed  Google Scholar 

  59. Lenehan B, Street J, O’Toole P, Siddiqui A, Poynton A (2009) Central cord syndrome in Ireland: the effect of age on clinical outcome. Eur Spine J 18(10):1458–1463

    Article  PubMed  PubMed Central  Google Scholar 

  60. Cifu DX, Seel RT, Kreutzer JS, McKinley WO (1999) A multicenter investigation of age-related differences in lengths of stay, hospitalization charges, and outcomes for a matched tetraplegia sample. Arch Phys Med Rehabil 80(7):733–740

    Article  CAS  PubMed  Google Scholar 

  61. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res 22(3):465–475

    Article  PubMed  Google Scholar 

  62. Alexandru D, So W (2012) Evaluation and management of vertebral compression fractures. Perm J 16(4):46–51

    Article  PubMed  PubMed Central  Google Scholar 

  63. Albrand G, Munoz F, Sornay-Rendu E, DuBoeuf F, Delmas PD (2003) Independent predictors of all osteoporosis-related fractures in healthy postmenopausal women: the OFELY study. Bone 32(1):78–85

    Article  CAS  PubMed  Google Scholar 

  64. Kim HJ, Yi JM, Cho HG et al (2014) Comparative study of the treatment outcomes of osteoporotic compression fractures without neurologic injury using a rigid brace, a soft brace, and no brace: a prospective randomized controlled non-inferiority trial. J Bone Joint Surg Am 96(23):1959–1966

    Article  PubMed  Google Scholar 

  65. Eck JC, Nachtigall D, Humphreys SC, Hodges SD (2008) Comparison of vertebroplasty and balloon kyphoplasty for treatment of vertebral compression fractures: a meta-analysis of the literature. Spine J 8(3):488–497

    Article  PubMed  Google Scholar 

  66. Anderson PA, Froyshteter AB, Tontz WL Jr (2013) Meta-analysis of vertebral augmentation compared with conservative treatment for osteoporotic spinal fractures. J Bone Miner Res 28(2):372–382

    Article  PubMed  Google Scholar 

  67. Guo JB, Zhu Y, Chen BL et al (2015) Surgical versus non-surgical treatment for vertebral compression fracture with osteopenia: a systematic review and meta-analysis. PLoS One 10(5):e0127145

    Article  PubMed  PubMed Central  Google Scholar 

  68. Goldstein CL, Chutkan NB, Choma TJ, Orr RD (2015) Management of the elderly with vertebral compression fractures. Neurosurgery 77(Suppl 4):S33–S45

    Article  PubMed  Google Scholar 

  69. Fassett DR, Harrop JS, Maltenfort M et al (2007) Mortality rates in geriatric patients with spinal cord injuries. J Neurosurg Spine 7(3):277–281

    Article  PubMed  Google Scholar 

  70. Hagen EM, Aarli JA, Gronning M (2005) The clinical significance of spinal cord injuries in patients older than 60 years of age. Acta Neurol Scand 112(1):42–47

    Article  CAS  PubMed  Google Scholar 

  71. Gulati A, Yeo CJ, Cooney AD, McLean AN, Fraser MH, Allan DB (2011) Functional outcome and discharge destination in elderly patients with spinal cord injuries. Spinal Cord 49(2):215–218

    Article  CAS  PubMed  Google Scholar 

  72. Furlan JC, Fehlings MG (2009) The impact of age on mortality, impairment, and disability among adults with acute traumatic spinal cord injury. J Neurotrauma 26(10):1707–1717

    Article  PubMed  PubMed Central  Google Scholar 

  73. Seel RT, Huang ME, Cifu DX, Kolakowsky-Hayner SA, McKinley WO (2001) Age-related differences in length of stays, hospitalization costs, and outcomes for an injury-matched sample of adults with paraplegia. J Spinal Cord Med 24(4):241–250

    Article  CAS  PubMed  Google Scholar 

  74. Werhagen L, Budh CN, Hultling C, Molander C (2004) Neuropathic pain after traumatic spinal cord injury--relations to gender, spinal level, completeness, and age at the time of injury. Spinal Cord 42(12):665–673

    Article  CAS  PubMed  Google Scholar 

  75. Aito S, D’Andrea M, Werhagen L et al (2007) Neurological and functional outcome in traumatic central cord syndrome. Spinal Cord 45(4):292–297

    CAS  PubMed  Google Scholar 

  76. DeVivo MJ, Kartus PL, Rutt RD, Stover SL, Fine PR (1990) The influence of age at time of spinal cord injury on rehabilitation outcome. Arch Neurol 47(6):687–691

    Article  CAS  PubMed  Google Scholar 

  77. New PW, Epi MC (2007) Influence of age and gender on rehabilitation outcomes in nontraumatic spinal cord injury. J Spinal Cord Med 30(3):225–237

    Article  PubMed  PubMed Central  Google Scholar 

  78. Golob JF Jr, Claridge JA, Yowler CJ, Como JJ, Peerless JR (2008) Isolated cervical spine fractures in the elderly: a deadly injury. J Trauma 64(2):311–315

    Article  PubMed  Google Scholar 

  79. Harris MB, Reichmann WM, Bono CM et al (2010) Mortality in elderly patients after cervical spine fractures. J Bone Joint Surg Am 92(3):567–574

    Article  PubMed  PubMed Central  Google Scholar 

  80. Barrett JJ, Putzke JD, Richards JS (2002) Early versus late onset of spinal cord injury among the elderly. J Clin Psychol Med 9(3):219–226

    Article  Google Scholar 

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Correspondence to Michael G. Fehlings MD, PhD, FRCSC, FACS .

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Witiw, C.D., Hachem, L.D., Fehlings, M.G. (2017). Spinal Injuries of the Elderly. In: Berhouma, M., Krolak-Salmon, P. (eds) Brain and Spine Surgery in the Elderly. Springer, Cham. https://doi.org/10.1007/978-3-319-40232-1_14

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