Abstract
With the advancement of endoscopy and tissue biopsy, cytology has had an appreciably diminished role in the diagnosis of neoplasms of the gastrointestinal tubal tract (oral cavity to anus). However, because cytology of the GI tract still has a few advantages over histology, cytolopathologists will continue to encounter a number of these specimens in their practice. Some of these advantages include sampling a wider surface area, reaching less accessible areas (e.g., strictured tubal segments), yielding better preserved materials, and having decreased risks of procedural complications. In fact, cytology is the main diagnostic modality in certain clinical scenarios such as infectious and submucosal lesions. In this chapter, the focus will be on exfoliative cytology specimens dealing with mucosal-based lesions (Table 4.1). For those obtained from fine needle aspiration, essentially from submucosal lesions (Table 4.2), refer to the corresponding chapters on salivary gland, lymphoid, neural, neuroendocrine and mesenchymal neoplasms. In addition, anal cytology will be discussed along with uterine cervical cytology in the appropriate section.
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Samedi, V.G., Bocklage, T. (2016). Gastrointestinal Tract. In: Pitfalls in Diagnostic Cytopathology With Key Differentiating Cytologic Features. Essentials in Cytopathology, vol 27. Springer, Cham. https://doi.org/10.1007/978-3-319-39809-9_4
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DOI: https://doi.org/10.1007/978-3-319-39809-9_4
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