Abstract
The total synthesis of terpene alkaloid natural products has received significant attention from the synthetic community in the last half-century. In recent years, however, synthetic interest in these targets has been reignited, in no small part due to the continued discovery of natural molecules bearing deviations from the classical steroid architecture. These findings have challenged the organic chemist toward new innovations in the preparation of these molecules.
Keywords
- Magnesium Sulfate
- Scintillation Vial
- Flash Chromatography
- Thin Layer Chromatography Analysis
- Complete Consumption
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Reprinted in part with permission from Sharpe, R. J.; Johnson, J. S. J. Am. Chem. Soc. 2015, 137, 4968, and Sharpe, R. J.; Johnson, J. S. J. Org. Chem. 2015, 80, 9740.
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- 1.
Partial and total synthetic studies on terpene alkaloids.
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Sharpe, R.J. (2016). Inception and Development of a Global and Local Desymmetrization Approach to the Synthesis of Steroidal Alkaloids: Stereocontrolled Total Synthesis of Paspaline. In: Stereoselective Desymmetrization Methods in the Assembly of Complex Natural Molecules. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-39025-3_3
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