Abstract
The morphology of abdominal aortic aneurysms (AAA) has been recognized as a factor that may predispose their rupture. The time variation of the AAA morphology induces hemodynamic changes in morphological behavior that, in turn, alters the distribution of hemodynamic stress on the arterial wall. This behavior can influence the phenomenon of rupture. In order to evaluate the relationship between the main geometric parameters characterizing the AAA and the hemodynamic stresses, 6 AAA models were reconstructed and characterized. The models were characterized using thirteen geometrical factors based on the lumen center line: eight 1D indices, three 3D indices, and two 0D indices. The temporal and spatial distributions of hemodynamic stresses were computed using computational fluid dynamics. The results showed that the hemodynamic stresses are modified by the time variations of the AAA morphology, and therefore, the hemodynamic stresses, in combination with other parameters, could be a criterion for improved rupture risk prediction. Statistical correlations between hemodynamic stresses and geometric indices have confirmed the influence by the AAA morphometry on the prediction of the rupture risks, although higher reliability of these correlations is required.
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References
Barrett, R., Berry, M., Chan, T., Demmel, J., Donato, J., Dongarra, J., Eijkhout, V., Pozo, R., Romine, C., der Vorst., H.V.: Templates for the Solution of Linear Systems: Building Blocks for Iterative Methods, 2 edn. SIAM, Philadelphia (1994)
Bordone, M.: Biodyn user manual. Tdyn: theoretical background. Technical Report, Compass (2012). Http://www.compassis.com/compass
Fillinger, M., Marra, S., Raghavan, M., Kennedy, F.: Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameter. J. Vasc. Surg. 37, 724–732 (2003)
Leung, J., Wright, A., Cheshire, K., Crane, J., Thom, S., Hughes, A., Xu, Y.: Fluid structure interaction of patient specific abdominal aortic aneurysm: a comparison with solid stress model. Biomed. Eng. Online 5 (33), (2006). doi: 10.1186/1475-925X-5-33
Papaharilaou, Y., Ekaterinaris, J., Manousaki, E., Katsamouris, A.: A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysm. J. Biomech. 40 (2), 367–377 (2007)
Pedersen, E., Kozerke, S., Ringgaard, S., Scheidegger, M., Boesiger, P.: Quantitative abdominal aortic flow measurements at controlled levels of ergometer exercise. Magn. Reson. Imaging 17 (4), 489–494 (1999)
Shum, J., Martufi, G., Dimartino, E., Washintong, C., Grisafi, J., Muluk, S., Finol, E.A.: Quantitative assessment of abdominal aortic aneurysm geometry. Ann. Biomed. Eng. 39 (1), 273–289 (2011)
Soudah, E., Vilalta, G., Bordone, M., Nieto, F., Vilalta, J., Vaquero, C.: Estudio paramétrico de tensiones hemodinámicas en modelos de aneurismas de aorta abdominal. Revista Internacional de Métodos Numéricos para Cálculo y Diseño en Ingeniería. 31 (2), 106–112 (2015)
Venkatasubramaniam, A., Fagan, M., Mehta, T., Mylankal, K., Ray, B., Kuhan, G., Chetter, I., McCollum., P.: A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms. Eur. J. Vasc. Endovasc. Surg. 28 (2), 168–176 (2004)
Vorp, D.A.: Biomechanics of abdominal aortic aneurysm. J. Biomech. 40, 1887–1902 (2007)
Vorp, D.A., Raghavan, M., Webster, M.: Mechanical wall stress in abdominal aortic aneurysm: influence of diameter and asymmetry. J. Vasc. Surg. 27 (4), 632–639 (1998)
Acknowledgements
The authors are grateful to the Fundação de Amparo à Pesquisa do Estado de Minas Gerais, (FAPEMIG)/Brazil, for its financial support for the publication of their research results.
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Alonso, G.V. et al. (2016). Preliminary Correlations for Characterizing the Morphology of Abdominal Aortic Aneurysms as Predictor of Rupture. In: Silva Neto, A., Llanes Santiago, O., Silva, G. (eds) Mathematical Modeling and Computational Intelligence in Engineering Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-38869-4_1
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DOI: https://doi.org/10.1007/978-3-319-38869-4_1
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