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The Impact of Uncontrolled Hypertension on the Heart

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Interventional Therapies for Secondary and Essential Hypertension

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

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Abstract

Available data indicate that raised blood pressure (BP) represents the greatest single contributor to the global burden of disease and to global mortality [1]. According to the results of a large meta-analysis that included about one million adults, each increase in systolic BP (SBP) of 20 mm Hg and/or each 10 mm Hg increase in diastolic BP (DBP) doubles the risk of fatal coronary events [2]. The relationship between BP and coronary heart disease (CHD) mortality may be recognized even below the traditional thresholds for hypertension (HTN), being evident over the BP range of 115/75–185/115 mm Hg; the increased risk is evident for all ages, although the absolute risk increases with increasing age. Several risk factors for CHD, such as dyslipidemia, diabetes mellitus, obesity, and sedentary habits, are frequently associated with HTN and contribute to the increased risk of CHD.

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Abbreviations

LVH:

Left ventricular hypertrophy

BP:

Blood pressure

CHD:

Coronary heart disease

DBP:

Diastolic blood pressure

HTN:

Hypertension

LV:

Left ventricular

SBP:

Systolic blood pressure

CV:

Cardiovascular

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Author information

Authors and Affiliations

  1. Department of Clinical and Experimental Sciences, University of Brescia, Owensboro, KY, USA

    Enrico Agabiti Rosei & Massimo Salvetti

  2. Department of Medicine, Azienda Spedali Civili di Brescia, European Society of Hypertension, Gardone Val Trompia, Italy

    Enrico Agabiti Rosei

Authors
  1. Enrico Agabiti Rosei
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  2. Massimo Salvetti
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Corresponding author

Correspondence to Enrico Agabiti Rosei .

Editor information

Editors and Affiliations

  1. First Cardiology Clinic, National and Kapodistrian University of Athens, Athens, Greece

    Costas Tsioufis

  2. Department of Nephrology and Hypertension, University Hospital Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany

    Roland E. Schmieder

  3. IRCCS Istituto Auxologico Italiano, University Milano-Bicocca, Milano Monza, Italy

    Giuseppe Mancia

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Agabiti Rosei, E., Salvetti, M. (2016). The Impact of Uncontrolled Hypertension on the Heart. In: Tsioufis, C., Schmieder, R., Mancia, G. (eds) Interventional Therapies for Secondary and Essential Hypertension. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-319-34141-5_7

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  • DOI: https://doi.org/10.1007/978-3-319-34141-5_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-34140-8

  • Online ISBN: 978-3-319-34141-5

  • eBook Packages: MedicineMedicine (R0)

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