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Dermatology in Public Health Environments pp 319–327Cite as

Basal Cell Carcinoma

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Abstract

Basal cell carcinoma (BCC) is the most incident type of skin cancer, having been related etiologically to chronic sun exposure and genetic predisposition. The classical clinical presentation of BCC is a slow-growing pearly papule, showing telangiectatic vessels that can progress to nodules. Different clinical and histologic subtypes are described, whose recognition is of great importance in arriving at the correct therapeutic decision and oncologic cure.

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Author information

Authors and Affiliations

  1. Santa Casa de Misericórdia Pontifical Catholic University of Paraná – PUCPR, Curitiba, Brazil

    Roberto Gomes Tarlé

  2. Santa Casa Hospital, Porto Alegre, Brazil

    Wagner Bertolini

  3. Instituto de Oncologia do Paraná, Curitiba, Brazil

    Luciano José Biasi

  4. Santa Casa de Curitiba, Instituto de Neurologia de Curitiba, Curitiba, Brazil

    José Roberto Toshio Shibue

Authors
  1. Roberto Gomes Tarlé
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  2. Wagner Bertolini
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  3. Luciano José Biasi
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  4. José Roberto Toshio Shibue
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Corresponding author

Correspondence to Roberto Gomes Tarlé .

Editor information

Editors and Affiliations

  1. Dermatology Service of Clinical, Hospital of Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

    Renan Rangel Bonamigo

  2. Health Secretary of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

    Sergio Ivan Torres Dornelles

Glossary

Confocal microscopy

Noninvasive imaging technique that enables in vivo visualization of the skin structure in real time.

Dermoscopy

Noninvasive diagnostic technique for the in vivo observation of skin lesions with a dermatoscope, allowing magnification of the lesion.

Gorlin’s syndrome

Also known as nevoid basal cell carcinoma syndrome, it is characterized by developmental anomalies, such as odontogenic keratocysts of the mandible, bifid ribs, palmoplantar pits and tumors, and especially multiple BCCs.

Mohs micrographic surgery

A microscopically controlled surgery used to treat different types of skin cancer, developed in 1938 by Frederic Mohs.

Optical coherence tomography

Noninvasive imaging examination that uses light waves to take cross-sectional pictures of the skin structure.

Photodynamic therapy

Treatment that uses a photosensitizer or photosensitizing agent that will be absorbed by the target cell, and a particular type of light that will react with the photosensitizer and cause cellular death.

PTCH1, patched 1 gene

This gene encodes the protein receptor for the sonic hedgehog, a molecule implicated in the formation of embryonic structures and in tumorigenesis. Mutations of this gene have been associated with basal cell nevus syndrome and sporadic BCC.

Telangiectasias

Dilated capillaries that appear clinically as red linear vessels with spidery appearance on the surface of the skin.

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Tarlé, R.G., Bertolini, W., Biasi, L.J., Shibue, J.R.T. (2018). Basal Cell Carcinoma. In: Bonamigo, R., Dornelles, S. (eds) Dermatology in Public Health Environments. Springer, Cham. https://doi.org/10.1007/978-3-319-33919-1_14

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  • DOI: https://doi.org/10.1007/978-3-319-33919-1_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33917-7

  • Online ISBN: 978-3-319-33919-1

  • eBook Packages: MedicineMedicine (R0)

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