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Antibody Detection: Principles and Applications

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Advanced Techniques in Diagnostic Microbiology

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Abstract

Antibody detection technologies have been developed to identify host response to the infectious agents or microorganisms and are widely used for the laboratory diagnosis of infectious diseases with improved sensitivity and specificity. In general, antibody detection methods have been utilized for detection and immune response of slow-growing, difficult-to-culture, uncultivatable, or emerging infectious agents, specifically certain viruses. Emerging antibody detection methods, such as rapid or handheld assay, antigen-antibody combination assay, as well as multiplexed flow cytometry, have been utilized in the clinical setting.

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Authors and Affiliations

  1. Emory University and Grady Memorial Hospital, Atlanta, GA, USA

    Yun F. (Wayne) Wang

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Correspondence to Yun F. (Wayne) Wang .

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  1. Departments of Laboratory Medicine and Internal Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Yi-Wei Tang

  2. Department of Pathology, Microbiology and Immunology and Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

    Charles W. Stratton

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(Wayne) Wang, Y.F. (2018). Antibody Detection: Principles and Applications. In: Tang, YW., Stratton, C. (eds) Advanced Techniques in Diagnostic Microbiology. Springer, Cham. https://doi.org/10.1007/978-3-319-33900-9_6

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