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Malignant Peripheral Nerve Sheath Tumors

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Atlas of Pediatric Brain Tumors

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Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) (ICD-O 9540/3) are rare soft-tissue sarcomas that arise predominantly from Schwann cells. A malignant spindle-cell tumor with histological, immunohistochemical, and ultrastructural features of Schwann cell differentiation, they usually arise in the setting of neurofibromatosis 1 (NF1) or may be seen sporadically in children.

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Author information

Authors and Affiliations

  1. Department of Pathology, Bagcilar Research and Training Hospital, Merkez Mah. Mimar Sinan Cad. 6 Sok, Bagcilar, Istanbul, Turkey

    Yazgi Koy M.D.

  2. Department of Pathology, Neuropathology Division, 505 Parnassus Avenue, Room M551, San Francisco, CA, 94143-0102, USA

    Tarik Tihan M.D., Ph.D.

Authors
  1. Yazgi Koy M.D.
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  2. Tarik Tihan M.D., Ph.D.
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Corresponding author

Correspondence to Tarik Tihan M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Pathology, Texas Children’s Hospital Baylor College of Medicine, Houston, Texas, USA

    Adekunle M. Adesina

  2. Department of Pathology, Neuropathology Division, San Francisco, California, USA

    Tarik Tihan

  3. Division of Pathology and Laboratory Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Virgin Islands, USA

    Christine E. Fuller

  4. PBTC Neuroimaging Center, Harvard Medical School, Boston, Massachusetts, USA

    Tina Young Poussaint

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© 2016 Springer International Publishing AG

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Koy, Y., Tihan, T. (2016). Malignant Peripheral Nerve Sheath Tumors. In: Adesina, A., Tihan, T., Fuller, C., Poussaint, T. (eds) Atlas of Pediatric Brain Tumors. Springer, Cham. https://doi.org/10.1007/978-3-319-33432-5_16

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  • DOI: https://doi.org/10.1007/978-3-319-33432-5_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33430-1

  • Online ISBN: 978-3-319-33432-5

  • eBook Packages: MedicineMedicine (R0)

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