Thrombocytopenia in the Surgical Intensive Care Unit

Chapter

Abstract

Thrombocytopenia is the most prevalent hematologic disorder in the ICU. Defined as a as a platelet count ≤150 × 109/L, thrombocytopenia is observed in 30–50 % of critically ill patients [1]. The consequences of thrombocytopenia range from a mild, asymptomatic phenomenon to microvascular failure. A drop in platelet count by >30 % is an independent risk factor for death and a stronger predictor of mortality than the Acute Physiology and Chronic Health Evaluation (APACHE) II score [2, 3]. Multiple etiologies may contribute to a low platelet count. This chapter will specifically review the diagnosis and management of thrombocytopenia in the surgical ICU patient.

Keywords

Thrombocytopenia Coagulopathy Heparin-induced thrombocytopenia 

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Copyright information

© Springer International Publishing Switzerland 2016

Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  1. 1.Department of Surgery, Beth Israel Deaconess Medical CenterBostonUSA
  2. 2.Division of Trauma, Surgical Critical Care, and Emergency Surgery, Department of SurgeryUniversity of PennsylvaniaPhiladelphiaUSA

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