Pruritus pp 351-354 | Cite as


  • Laurent MiseryEmail author


Capsaicin is extracted from the hot pepper plant. Its use is ancient but the understanding of its effects is relatively new. Capsaicin is a ligand of TRPV1, which appears to be involved in many burning itchings. Capsaicin is traded in some countries but it has to be prepared by pharmacists in many countries. A new patch containing 8 % of capsaicin is now available but its use is restricted to specialized centres. Research about other TRPV1 antagonists with less side effects is dynamic.


Itch Pruritus Capsaicin TRP Vanilloid Paresthesia Diabetes Zoster Nerve Neuropathic Pain 


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Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  1. 1.Laboratory of Neurosciences of Brest, and Department of DermatologyUniversity Hospital, and University of BrestBrestFrance

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