Pruritus is an important symptom of inflammatory skin diseases as local inflammatory mechanisms may induce neurogenic inflammation and subsequent itch. Mild to severe pruritus accompanies numerous inflammatory skin disorders including, but not limited to atopic dermatitis, eczema, psoriasis, pemphigoid or lichen planus. The frequency of pruritus in skin diseases may vary depending on the entity and studied population. Many aspects of pruritus in inflammatory cutaneous conditions, like psoriasis still remains unclarified and further clinical and molecular studies on itching have to be performed in the near future to elaborate more specific and efficacious antipruritic therapies.
KeywordsPsoriasis Neurogenic inflammation Treatment Dermatologic pruritus
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