Abstract
The pharmacokinetic characteristics of ethosuximide are described and the interaction effects of concomitant antiepileptic drugs on ethosuximide in terms of its pharmacokinetics and pharmacodynamics are highlighted.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Giaccone M, Bartoli A, Gatti G, Marchiselli R, Pisani F, Latella MA, Perucca E. Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients. Br J Clin Pharmacol. 1996;41:575–9.
Eriksson AS, Hoppu K, Nergardh A, Boreu L. Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy. Epilepsia. 1996;37:769–73.
Kasteleijn-Nolst Trenite DGA, Marescaux C, Stodieck S, Edelbroek PM, Oosting J. Evaluation of the piracetam analogue, levetiracetam. Epilepsy Res. 1996;25:225–30.
Battino D, Cusi C, Franceschetti S, Moise A, Spina S, Avanzini G. Ethosuximide plasma concentrations: influence of age and associated concomitant therapy. Clin Pharmacokinet. 1982;7:176–80.
Loiseau P, Duché B. Rolandic paroxysmal epilepsy or partial benign epilepsy in children. Rev Prat. 1988;38:1194–6.
Pisani F, Narbone MC, Trunfio C, Fazio A, La Rosa G, Oteri G, Di Perri R. Valproic acid-ethosuximide interaction: a pharmacokinetic study. Epilepsia. 1984;25:229–33.
Rowan AJ, Meijer JW, de Beer-Pawlikowski N, van der Geest P, Meinardi H. Valproate-ethosuximide combination therapy for refractory seizures. Arch Neurol. 1983;40:797–802.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Patsalos, P.N. (2016). Ethosuximide. In: Antiepileptic Drug Interactions. Springer, Cham. https://doi.org/10.1007/978-3-319-32909-3_7
Download citation
DOI: https://doi.org/10.1007/978-3-319-32909-3_7
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-32908-6
Online ISBN: 978-3-319-32909-3
eBook Packages: MedicineMedicine (R0)