Skip to main content

Omental Transplant for Revascularization in Critical Ischemic Limbs and Tissues

  • Chapter
  • First Online:
Critical Limb Ischemia

Abstract

Salvage of of chronic isheamic limbs affected by Buerger’s disease has been a dilemma for surgeons. Reconstructive procedures are usually not possible as graft patency rates are low. Limb amputation often is the only available management option left.Angiogenic properties of omentum were used to salvage these chronic ischemic limbs. Omentum, due to presence of CD3-4 + and Ly-1B stem cells with power to migrate, establishes biological anastomosis on its own between capillaries of omentum and ischemic tissue capillaries within 3 days along with retrograde filling of original vessels and/or neovascularisation. In Agarwal Technique, omentum is lengthened in continuity so as to reach the affected limb and provide the needed vascularity. We have a follow up of 15 years with 85% salvage of limbs in over 800 patients.Uses of omentum in other surgical situations is also highlighted.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Morrison R. Remarks on some functions of the omentum. Br J Med. 1906;1:76.

    Article  Google Scholar 

  2. Shaughnessy L. An experimental method of providing a collateral circulation to the heart. Br J Surg. 1936;23:665.

    Article  Google Scholar 

  3. Turner-Warwick R. The use of omental pedical graft in urinary tract reconstruction. J Urol. 1976;116:341.

    CAS  PubMed  Google Scholar 

  4. Goldsmith HS, De los Santos R. Omental transposition for the treatment of chronic lymphedema. Rev Surg. 1966;23:303.

    CAS  PubMed  Google Scholar 

  5. Casten DF, Alday ES. Omental transfer for revascularisation of the extremities. Surg Gynecol Obstet. 1971;132:301.

    CAS  PubMed  Google Scholar 

  6. Vineberg A, Lwin MM. Fostering a natural artery bypass for disseminated coronary artery disease by pericoronory omental strips. Surg Gynecol Obstet. 1973;137:565.

    CAS  PubMed  Google Scholar 

  7. Carter DC, Jenkins DHR, Whitfield HN. Omental re-inforcement of intestinal anastomosis and experimental study in the rabbit. Br J Surg. 1972;59:129.

    Article  CAS  PubMed  Google Scholar 

  8. Agarwal VK, Agarwal S. Omental allograft: its role in revascularization of ischemic limbs with special reference to the Buerger’s disease—a clinical and experimental study. In: Masutomo A, DeBakey ME, Kondo J, editors. Advances cardiovascular surgery. New York: Elsevier; 1991. p. 89–96.

    Google Scholar 

  9. Solvason N, Kearney JF. The human fetal omentum: a site of B cell generation. J Exp Med. 1992;175(2):397–404.

    Article  CAS  PubMed  Google Scholar 

  10. Solvoson N, Chen X, Shu F, Kearney JF. The fetal omentum in mice and human. A site enriched for precursor of Cd5 B cells early in development. Ann N Y Acad Sci. 1992;651:10–20.

    Article  Google Scholar 

  11. García-Gómez I, et al. Angiogenic capacity of human omental cells. Neurol Res. 2005;27(8):807–11.

    Article  PubMed  Google Scholar 

  12. Murie JA. Short practice of surgery. 23rd ed. London: Arnold; 2000.

    Google Scholar 

  13. Agarwal VK. Long term results of omental transplantation in chronic occlusive arterial disease (Buerger’s disease) and retinal avascular diseases (retinitis pigmentosa). Int Surg. 2007;92:174–83.

    PubMed  Google Scholar 

  14. Hoshino S, Nakayama K, Igari T, Honda K. Long term results of omental transplantation for chronic occlusive arterial diseases. Int Surg. 1983;68:47–50.

    CAS  PubMed  Google Scholar 

  15. Talwar S, Jain S, Parwal R, Laddha BL, Prashad P. Pedical omental transfer for limb salvage in Buerger’s disease. Int J Cardiol. 2002;72:127–32.

    Article  Google Scholar 

  16. Nishimura A, Sano F, Nakanishi Y. Omental transplantation for relief of limb ischaemia. Surg Forum. 1977;28:213–5.

    CAS  PubMed  Google Scholar 

  17. Hoshino S, Hamada O, Iwaya F, Takahira H, Honda K. Omental transplantation for chronic occlusive arterial diseases. Int Surg. 1979;64:21–9.

    CAS  PubMed  Google Scholar 

  18. Heckenlively JR, Silver J. Management and treatment of retinitis pigmentosa. In: Heckenlively JR, editor. Retinitis pigmentosa. London: J.B. Lippincott; 1988. p. 90–106.

    Google Scholar 

  19. Humayun MS, Weiland JD, De Juan Jr E. Artificial vision. In: Peyman GA, Meffer SA, Conway MD, et al., editors. Viteroretinal surgical techniques. London: Martin Dunitz; 2001, p. 579–82.

    Google Scholar 

  20. Goldsmith HS, Chen WF, Palena PV. Intact omentum for ocular vascularization. Invest Opthalmol. 1975;14:163–5.

    CAS  Google Scholar 

  21. Agarwal VK, Hardia PS. Pedicle omental transplant. In: Catlin RB, editor. Retinal degeneration: causes, diagnosis and treatment. Nova Science; 2009. 978-1-60741-007-2.

    Google Scholar 

  22. Sen PK, et al. Transmyocardial acupuncture: a new approach to myocardial revascularization. J Thorac Cardiovas Surg. 1965;50:181–9.

    CAS  Google Scholar 

  23. Agarwal VK. Myocardial revascularization by pedicled omentopexy and transmyocardial acupuncture an experimental study in dogs. Saudi Heart J. 1996;7(1):49–54.

    Google Scholar 

  24. McLacblin AD, Olsson IS, Pill DF. Anterior anastomosis of the rectosigmoid colon: an experimental study. Surgery. 1976;800:306.

    Google Scholar 

  25. Kiricuta I, Goldstein AMB. The repair of extensive vesico-vaginal fistula with pedicled omentum: review of 27 cases. J Urol. 1972;104:724.

    Google Scholar 

  26. Tiptaft RC, Costello AJ, Paris AMI. The long term follow up of retroperitoneal fibrosis. Br J Urol. 1982;54:630.

    Google Scholar 

  27. Turner-Warwick R. Complex traumatic posterior urethral strictures. J Urol. 1977;118:564.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Agarwal, V.K., Bindal, J., Bhargava, S. (2017). Omental Transplant for Revascularization in Critical Ischemic Limbs and Tissues. In: Dieter, R., Dieter, Jr, R., Dieter, III, R., Nanjundappa, A. (eds) Critical Limb Ischemia. Springer, Cham. https://doi.org/10.1007/978-3-319-31991-9_42

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-31991-9_42

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31989-6

  • Online ISBN: 978-3-319-31991-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics