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Preparation of Methylene-Substituted Calixarenes

  • Silvio E. BialiEmail author
Chapter

Abstract

The different synthetic approaches for the preparation of “classical” calixarenes with one, part, or all bridges chemically modified are reviewed. The methods include the cyclization of fragments, the homologous anionic ortho Fries rearrangement, the spirodienone method, the lithiation/alkylation approach, the oxidation of the bridges followed by reaction of the carbonyl units with organolithium reagents, and the bromination of the bridges followed by reaction with nucleophiles.

Keywords

Synthesis Calixarenes Cyclophanes Oxidation Bromination 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Institute of ChemistryThe Hebrew University of JerusalemJerusalemIsrael

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