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Lethal Hereditary Vascular Disorders: Osler-Weber-Rendu Syndrome, Ataxia-Telangiectasia, and Fabry’s Disease

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Deadly Dermatologic Diseases

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Abstract

Mucocutaneous vascular ectasia, otherwise referred to as telangiectasia, can be an important harbinger of serious systemic disease. Among a variety of acquired conditions, including hepatic cirrhosis, that are responsible for their development, are a heterogeneous group of inherited conditions that entail the development of multiple cutaneous and mucous membrane vascular lesions associated with other life-threatening complications. This chapter deals with the clinical and pathologic features of three such conditions, namely, Osler-Weber-Rendu (OWR) syndrome, ataxia-telangiectasia (AT), and Fabry’s disease (FD).

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References

OWR

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Author information

Authors and Affiliations

  1. Director of Dermatopathology, Dermatology Specialists of Florida, Panama City, FL, USA

    Michael B. Morgan

  2. Staff Dermatopathologist, Advanced Dermatology and Cosmetic Surgery, Clermont, FL, USA

    Michael B. Morgan

  3. Professor of Dermatology, Michigan State College of Medicine, East Lancing, USA

    Michael B. Morgan

Authors
  1. Garone Michael
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  2. Michael B. Morgan
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Correspondence to Michael B. Morgan .

Editor information

Editors and Affiliations

  1. Assistant Professor Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

    David R. Crowe

  2. Dermpath Diagnostics, Tampa, Florida, USA

    Michael Morgan

  3. MetroHealth Medical Center, Cleveland, Ohio, USA

    Stephen Somach

  4. Washington, District of Columbia, USA

    Kara Trapp

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Michael, G., Morgan, M.B. (2016). Lethal Hereditary Vascular Disorders: Osler-Weber-Rendu Syndrome, Ataxia-Telangiectasia, and Fabry’s Disease. In: Crowe, D., Morgan, M., Somach, S., Trapp, K. (eds) Deadly Dermatologic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-31566-9_15

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  • DOI: https://doi.org/10.1007/978-3-319-31566-9_15

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31564-5

  • Online ISBN: 978-3-319-31566-9

  • eBook Packages: MedicineMedicine (R0)

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