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The Cnidaria, Past, Present and Future pp 347–357Cite as

Association of Coral-Microbes, and the Ecological Roles of Microbial Symbionts in Corals

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Abstract

Corals are sessile marine invertebrates and they form a unique ecosystem, which supports diverse marine organisms. They host a wide variety of microorganisms such as bacteria, archaea and fungi. The interactions between corals and associated microbes are likely to play an important role in coral health. These microbial communities respond and quickly adapt to changes and also have central roles in ecological function. They are also involved in the biogeochemical cycling, particularly nitrogen, sulfur, phosphorus as well as in host defense. A complex web of interactions exists between the coral-associated microbes and each of them is linked with one another. So, characterizing these links is fundamental to understand coral reef resilience and to improve to predict ecological change. The culture-independent methods have recorded high proportions of novel coral-associated microbes and also species-specific microbial communities. Metagenomics-based investigations have also revealed the dynamics in the genomic diversity of the microbes upon environmental changes. Eventhough, their complete roles are not currently accounted and only less culturable microbes have been isolated, especially from the stony corals. So, it is necessary to develop novel techniques to increase the culturables as well as explore the shaping factors of coral-associated microbes and their central functions in corals.

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References

  • Ainsworth TD, Thurber RV, Gates RD et al (2010) The future of coral reefs: a microbial perspective. Trends Ecol Evol 25:233–240

    Article  PubMed  Google Scholar 

  • Alagely A, Krediet CJ, Ritchie KB et al (2011) Signaling-mediated cross-talk modulates swarming and biofilm formation in a coral pathogen Serratia marcescens. ISME J 5:1609–1620

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Amend AS, Barshis DJ, Oliver TA (2012) Coral-associated marine fungi form novel lineages and heterogeneous assemblages. ISME J 6:1291–1301

    Article  CAS  PubMed  Google Scholar 

  • Beman JM, Roberts KJ, Wegley L et al (2007) Distribution and diversity of archaeal ammonia monooxygenase (amoA) genes associated with corals. Appl Environ Microbiol 73:5642–5647

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bentis CJ, Kaufman L, Golubic S et al (2000) Endolithic fungi in reef-building corals (Order:Scleractinia) are common, cosmopolitan, and potentially pathogenic. Biol Bull 198:254–260

    Article  CAS  PubMed  Google Scholar 

  • Bourne DG, Munn CB (2005) Diversity of bacteria associated with the coral Pocillopora damicornis from the Great Barrier Reef. Environ Microbiol 7:1162–1174

    Article  CAS  PubMed  Google Scholar 

  • Bourne D, Iida Y, Uthicke S et al (2008) Changes in coral-associated microbial communities during a bleaching event. ISME J 2:350–363

    Article  CAS  PubMed  Google Scholar 

  • Bourne DG, Dennis PG, Uthicke S et al (2013) Coral reef invertebrate microbiomes correlate with the presence of photosymbionts. ISME J 7:1452–1458

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Broadbent AD, Jones GB (2004) DMS and DMSP in mucus ropes, coral mucus, surface films and sediment pore waters from coral reefs in the Great Barrier Reef. Mar Freshw Res 55:849–855

    Article  CAS  Google Scholar 

  • Brown BE, Bythell JC (2005) Perspectives on mucus secretion in reef corals. Mar Ecol Prog Ser 296:291–309

    Article  CAS  Google Scholar 

  • Carlos C, Castro DBA, Ottoboni LMM et al (2014) Comparative metagenomic analysis of coral microbial communities using a reference-independent approach. PLoS One 9:e111626

    Article  PubMed  PubMed Central  Google Scholar 

  • Chen CP, Tseng CH, Chen CA et al (2011) The dynamics of microbial partnerships in the coral Isopora palifera. ISME J 5:728–740

    Article  CAS  PubMed  Google Scholar 

  • Chen M, Shao CL, Fu XM et al (2013) Bioactive indole alkaloids and phenyl ether derivatives from a marine-derived Aspergillus sp. fungus. J Nat Prod 76:547–553

    Article  CAS  PubMed  Google Scholar 

  • Chen M, Shao CL, Meng H et al (2014a) Anti-respiratory syncytial virus prenylated dihydroquinolone derivatives from the gorgonian-derived fungus Aspergillus sp. XS-20090B15. J Nat Prod 77:2720–2724

    Article  PubMed  Google Scholar 

  • Chen M, Shao CL, Fu XM et al (2014b) Lumazine peptides penilumamides B-D and the cyclic pentapeptide asperpeptide A from a gorgonian-derived Aspergillus sp. fungus. J Nat Prod 77:1601–1606

    Article  CAS  PubMed  Google Scholar 

  • Chimetto LA, Brocchi M, Thompson CC et al (2008) Vibrios dominate as culturable nitrogen-fixing bacteria of the Brazilian coral Mussismilia hispida. Syst Appl Microbiol 31:312–319

    Article  CAS  PubMed  Google Scholar 

  • Closek CJ, Sunagawa S, DeSalvo MK et al (2014) Coral transcriptome and bacterial community profiles reveal distinct Yellow Band Disease states in Orbicella faveolata. ISME J 8:2411–2422

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cooney RP, Pantos O, Le Tissier MDA et al (2002) Characterization of the bacterial consortium associated with black band disease in coral using molecular microbiological techniques. Environ Microbiol 4:401

    Article  PubMed  Google Scholar 

  • de Castro AP, Araújo SD Jr, Reis AM et al (2010) Bacterial community associated with healthy and diseased reef coral Mussismilia hispida from eastern Brazil. Microb Ecol 59:658–667

    Article  PubMed  Google Scholar 

  • Dinsdale EA, Pantos O, Smriga S et al (2008) Microbial ecology of four coral atolls in the Northern Line Islands. PLoS One 3:e1584

    Article  PubMed  PubMed Central  Google Scholar 

  • Dobretsov S, Qian P (2004) The role of epibotic bacteria from the surface of the soft coral Dendronephthya sp. in the inhibition of larval settlement. J Exp Mar Biol Ecol 299:35–50

    Article  Google Scholar 

  • Freiwald A, Reitner J, Krutschinna J et al (1997) Microbial alteration of the deep-water coral Lophelia pertusa: early postmortem processes. Facies 36:223–226

    Google Scholar 

  • Frias-Lopez J, Zerkle AL, Bonheyo GT et al (2002) Partitioning of bacterial communities between seawater and healthy, black band diseased, and dead coral surfaces. Appl Environ Microbiol 68:2214–2228

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gantar M, Kaczmarsky LT, Stanic D et al (2011) Antibacterial activity of marine and black band disease cyanobacteria against coral associated bacteria. Mar Drugs 9:2089–2105

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Golubic S, Radtke G, LeCampion-Alsumard TL et al (2005) Endolithic fungi in marine ecosystems. Trends Microbiol 13:229–235

    Article  CAS  PubMed  Google Scholar 

  • Harder T, Lau SCK, Dobretsov S et al (2003) A distinctive epibiotic bacterial community on the soft coral Dendronephthya sp. and antibacterial activity of coral tissue extracts suggest a chemical mechanism against bacterial epibiosis. FEMS Microbiol Ecol 43:337–347

    Article  CAS  PubMed  Google Scholar 

  • Hong MJ, Yu YT, Chen CA et al (2009) Influence of species specificity and other factors on bacteria associated with the coral Stylophora pistillata in Taiwan. Appl Environ Microbiol 75:7797–7806

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ivanova EP, Bowman JP, Lysenko AM et al (2005) Erythrobacter vulgaris sp. nov., a novel organism isolated from the marine invertebrates. Syst Appl Microbiol 28:123–130

    Article  CAS  PubMed  Google Scholar 

  • Kellogg CA (2004) Tropical Archaea: diversity associated with the surface microlayer of corals. Mar Ecol Prog Ser 273:81–88

    Article  CAS  Google Scholar 

  • Kellogg CA, Lisle J, Galkiewicz JP et al (2009) Culture-independent characterization of bacterial communities associated with the cold-water coral Lophelia pertusa in the northeastern Gulf of Mexico. Appl Environ Microbiol 75:2294–2303

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kendrick B, Risk MJ, Michaelides J et al (1982) Amphibious microborers: bioeroding fungi isolated from live corals. Bull Mar Sci 32:862–867

    Google Scholar 

  • Kimes NE, Van Nostrand JD, Weil E et al (2010) Microbial functional structure of Montastraea faveolata, an important Caribbean reef-building coral, differs between healthy and yellow-band diseased colonies. Environ Microbiol 12:541–556

    Article  CAS  PubMed  Google Scholar 

  • Kooperman N, Ben-Dov E, Kramarsky-Winter E et al (2007) Coral mucus-associated bacterial communities from natural and aquarium environments. FEMS Microbiol Lett 276:106–113

    Article  CAS  PubMed  Google Scholar 

  • Krediet CJ, Ritchie KB, Paul VJ et al (2013) Coral-associated micro-organisms and their roles in promoting coral health and thwarting diseases. Proc R Soc B Biol Sci 280:20122328

    Article  Google Scholar 

  • Kvennefors EC, Sampayo E, Ridgway T et al (2010) Bacterial communities of two ubiquitous Great Barrier Reef corals reveals both site- and species-specificity of common bacterial associates. PLoS One 29:e10401

    Article  Google Scholar 

  • Kvennefors EC, Sampayo E, Kerr C et al (2012) Regulation of bacterial communities through antimicrobial activity by the coral holobiont. Microb Ecol 63:605–618

    Article  CAS  PubMed  Google Scholar 

  • Lampert Y, Kelman D, Dubinsky Z et al (2006) Diversity of culturable bacteria in the mucus of the Red Sea coral Fungia scutaria. FEMS Microbiol Ecol 58:99–108

    Article  CAS  PubMed  Google Scholar 

  • LeCampion-Alsumard T, Golubic S, Priess K et al (1995) Fungi in corals–symbiosis or disease–interaction between polyps and fungi causes pearl-like skeleton biomineralization. Mar Ecol Prog Ser 117:137–147

    Article  Google Scholar 

  • Lema KA, Willis BL, Bourne DG et al (2012) Corals form characteristic associations with symbiotic nitrogenfixing bacteria. Appl Environ Microbiol 78:3136–3144

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lesser MP, Mazel CH, Gorbunov MY et al (2004) Discovery of symbiotic nitrogen-fixing cyanobacteria in corals. Science 305:997–1000

    Article  CAS  PubMed  Google Scholar 

  • Li HJ, Xie YL, Xie ZL et al (2012) Chondrosterins A-E, triquinane-type sesquiterpenoids from soft coral-associated fungus Chondrostereum sp. Mar Drugs 10:627–638

    Article  PubMed  PubMed Central  Google Scholar 

  • Li HJ, Chen T, Xie YL et al (2013) Isolation and structural elucidation of chondrosterins F-H from the marine fungus Chondrostereum sp. Mar Drugs 11:551–558

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li J, Chen Q, Long LJ et al (2014a) Bacterial dynamics within the mucus, tissue and skeleton of the coral Porites lutea during different seasons. Sci Rep 4:07320

    Article  CAS  Google Scholar 

  • Li J, Zhong M, Lei X et al (2014b) Diversity and antibacterial activities of culturable fungi associated with coral Porites pukoensis. World J Microbiol Biotechnol 30:2551–2558

    Article  CAS  PubMed  Google Scholar 

  • Littman R, Willis BL, Bourne DG et al (2011) Metagenomic analysis of the coral holobiont during a natural bleaching event on the Great Barrier Reef. Environ Microbiol Rep 3:651–660

    Article  CAS  PubMed  Google Scholar 

  • Liu Z, Xia G, Chen S et al (2014) Eurothiocin A and B, sulfur-containing benzofurans from a soft coral-derived fungus Eurotium rubrum SH-823. Mar Drugs 12:3669–3680

    Article  PubMed  PubMed Central  Google Scholar 

  • Meron D, Atias E, Kruh LI et al (2011) The impact of reduced pH on the microbial community of the coral Acropora eurystoma. ISME J 5:51–60

    Article  PubMed  Google Scholar 

  • Meron D, Rodolfo-Metalpa R, Cunning R et al (2012) Changes in coral microbial communities in response to a natural pH gradient. ISME J 6:1775–1785

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mouchka ME, Hewson I, Harvell CD et al (2010) Coral-associated bacterial assemblages: current knowledge and the potential for climate-driven impacts. Integr Comp Biol 50:662–674

    Article  PubMed  Google Scholar 

  • Nedashkovskaya OI, Kim SB, Lysenko AM et al (2005) Bizionia paragorgiae gen. nov., sp. nov., a novel member of the family Flavobacteriaceae isolated from the soft coral Paragorgia arborea. Int J Syst Evol Microbiol 55:375–378

    Article  CAS  PubMed  Google Scholar 

  • Neulinger SC, Jarnegren J, Ludvigsen M et al (2008) Phenotype-specific bacterial communities in the coldwater coral Lophelia pertusa (Scleractinia) and their implications for the coral’s nutrition, health, and distribution. Appl Environ Microbiol 74:7272–7285

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Nithyanand P, Pandian SK (2009) Phylogenetic characterization of culturable bacterial diversity associated with the mucus and tissue of the coral Acropora digitifera from the Gulf of Mannar. FEMS Microbiol Ecol 69:384–394

    Article  CAS  PubMed  Google Scholar 

  • Nithyanand P, Manju S, Pandian SK (2011) Phylogenetic characterization of culturable actinomycetes associated with the mucus of the coral Acropora digitifera from Gulf of Mannar. FEMS Microbiol Lett 314:112–118

    Article  CAS  PubMed  Google Scholar 

  • Pantos O, Cooney RP, Le Tissier MDA et al (2003) The bacterial ecology of a plague-like disease affecting the Caribbean coral Montastrea annularis. Environ Microbiol 5:370–382

    Article  CAS  PubMed  Google Scholar 

  • Priess K, Le Campion-Alsumard T, Golubic S et al (2000) Fungi in corals: black bands and density-banding of Porites lutea and P. lobata skeleton. Mar Biol 136:19–27

    Article  Google Scholar 

  • Raina JB, Tapiolas D, Willis BL et al (2009) Coral-associated bacteria and their role in the biogeochemical cycling of sulfur. Appl Environ Microbiol 75:3492–3501

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Raina JB, Dinsdale E, Willis BL et al (2010) Do organic sulphur compounds DMSP and DMS drive coral microbial associations? Trends Microbiol 18:101–108

    Article  CAS  PubMed  Google Scholar 

  • Reis AM, Araújo SD Jr, Moura RL et al (2009) Bacterial diversity associated with the Brazilian endemic reef coral Mussismilia braziliensis. J Appl Microbiol 106:1378–1387

    Article  CAS  PubMed  Google Scholar 

  • Ritchie KB (2006) Regulation of microbial populations by coral surface mucus and mucus-associated bacteria. Mar Ecol Prog Ser 322:1–14

    Article  CAS  Google Scholar 

  • Ritchie KB, Smith GW (1998) Type II white-band disease. Rev Biol Trop 46:199–203

    Google Scholar 

  • Rohwer F, Kelley S (2004) Culture independent analysis of coral-associated microbes. In: Loya Y, Rosenberg E (eds) Coral health and disease. Springer, New York, pp 265–277

    Chapter  Google Scholar 

  • Rohwer F, Breitbart M, Jara J et al (2001) Diversity of bacteria associated with the Caribbean coral Montastrea franksi. Coral Reefs 20:85–91

    Article  Google Scholar 

  • Rohwer F, Seguritan V, Azam F et al (2002) Diversity and distribution of coral-associated bacteria. Mar Ecol Prog Ser 243:1–10

    Article  Google Scholar 

  • Rosenberg E, Koren O, Reshef L et al (2007) The role of microorganisms in coral health, disease and evolution. Nat Rev Microbiol 5:355–362

    Article  CAS  PubMed  Google Scholar 

  • Schottner S, Hoffman F, Wild C et al (2009) Inter- and intra-habitat bacterial diversity associated with cold-water corals. ISME J 3:756–759

    Article  PubMed  Google Scholar 

  • Sekar R, Mills DK, Remily ER et al (2006) Microbial communities in the surface mucopolysaccharide layer and the black band microbial mat of black band-diseased Siderastrea siderea. Appl Environ Microbiol 72:5963–5973

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shao CL, Wu HX, Wang CY et al (2011) Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod 74:629–633

    Article  CAS  PubMed  Google Scholar 

  • Shao CL, Wang CY, Wei MY et al (2013) Aspergilones A and B, two benzylazaphilones with an unprecedented carbon skeleton from the gorgonian-derived fungus Aspergillus sp. Bioorg Med Chem Lett 21:690–693

    Article  Google Scholar 

  • Shashar N, Cohen Y, Loya Y et al (1994) Nitrogen fixation (acetylene reduction) in stony corals: evidence for coral-bacteria interactions. Mar Ecol Prog Ser 111:259–264

    Article  CAS  Google Scholar 

  • Shinzato C, Shoguchi E, Kawashima T et al (2011) Using the Acropora digitifera genome to understand coral responses to environmental change. Nature 476:320–323

    Article  CAS  PubMed  Google Scholar 

  • Shnit-Orland M, Kushmaro A (2009) Coral mucus associated bacteria: a possible first line of defense. FEMS Microbiol Ecol 67:371–380

    Article  CAS  PubMed  Google Scholar 

  • Shnit-Orland M, Sivan A, Kushmaro A (2012) Antibacterial activity of Pseudoalteromonas in the coral holobiont. Microb Ecol 4:851–859

    Article  Google Scholar 

  • Siboni N, Ben-Dov E, Sivan A et al (2008) Global distribution and diversity of coral-associated Archaea and their possible role in the coral holobiont nitrogen cycle. Environ Microbiol 10:2979–2990

    Article  CAS  PubMed  Google Scholar 

  • Sun W, Peng C, Zhao Y et al (2012) Functional gene-guided discovery of type II polyketides from culturable actinomycetes associated with soft coral Scleronephthya sp. PLoS One 7:e42847

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Teplitski M, Ritchie K (2009) How feasible is the biological control of coral diseases? Trends Ecol Evol 24:378–385

    Article  PubMed  Google Scholar 

  • Thomas S, Burdett H, Temperton B et al (2010) Evidence for phosphonate usage in the coral holobiont. ISME J 4:459–461

    Article  CAS  PubMed  Google Scholar 

  • Thurber RV, Willner-Hall D, Rodriguez-Mueller B et al (2009) Metagenomic analysis of stressed coral holobionts. Environ Microbiol 11:2148–2163

    Article  CAS  Google Scholar 

  • Tringe SG, von Mering C, Kobayashi A et al (2005) Comparative metagenomics of microbial communities. Science 308:554–557

    Article  CAS  PubMed  Google Scholar 

  • Trisuwan K, Rukachaisirikul V, Kaewpet M et al (2011) Sesquiterpene and xanthone derivatives from the sea fan-derived fungus Aspergillus sydowii PSU-F154. J Nat Prod 74:1663–1667

    Article  CAS  PubMed  Google Scholar 

  • Van Alstyne KL, Schupp P, Stattery M (2006) The distribution of dimethylsulfoniopropionate in tropical Pacific coral reef invertebrates. Coral Reefs 25:321–327

    Article  Google Scholar 

  • Vega Thurber R, Willner-Hall D, Rodriguez-Mueller B et al (2009) Metagenomic analysis of stressed coral holobionts. Environ Microbiol 11:2148–2163

    Article  PubMed  Google Scholar 

  • Webster NS, Bourne D (2007) Bacterial community structure associated with the Antarctic soft coral, Alcyonium antarcticum. FEMS Microbiol Ecol 59:81–94

    Article  CAS  PubMed  Google Scholar 

  • Webster NS, Smith LD, Heyward AJ et al (2004) Metamorphosis of a Scleractinian coral in response to microbial biofilms. Appl Environ Microbiol 70:1213–1221

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wegley L, Yu Y, Breitbart M (2004) Coral-associated archaea. Mar Ecol Prog Ser 273:89–96

    Article  CAS  Google Scholar 

  • Wegley L, Edwards RA, Rodriguez-Brito B et al (2007) Metagenomic analysis of the microbial community associated with the coral Porites astreoides. Environ Microbiol 9:2707–2719

    Article  CAS  PubMed  Google Scholar 

  • Wei MY, Wang CY, Liu QA et al (2010) Five sesquiterpenoids from a marine-derived fungus Aspergillus sp. isolated from a gorgonian Dichotella gemmacea. Mar Drugs 8:941–949

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wei MY, Li D, Shao CL et al (2013) (±)-Pestalachloride D, an antibacterial racemate of chlorinated benzophenone derivative from a soft coral-derived fungus Pestalotiopsis sp. Mar Drugs 11:1050–1060

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wild C, Rasheed M, Werner U et al (2004) Degradation and mineralization of coral mucus in reef environments. Mar Ecol Prog Ser 267:159–171

    Article  Google Scholar 

  • Williams WM, Viner AB, Broughton WJ (1987) Nitrogen fixation (acetylene reduction) associated with the living coral Acropora variabilis. Mar Biol 94:531–535

    Article  Google Scholar 

  • Yakimov MM, Cappello S, Crisafi E et al (2006) Phylogenetic survey of metabolically active microbial communities associated with the deep-sea coral Lophelia pertusa from the Apulian plateau, Central Mediterranean Sea. Deep-Sea Res 53:62–75

    Article  Google Scholar 

  • Yang S, Sun W, Tang C et al (2013a) Phylogenetic diversity of Actinobacteria associated with soft coral Alcyonium gracllimum and stony coral Tubastraea coccinea in the East China Sea. Microb Ecol 66:189–199

    Article  PubMed  Google Scholar 

  • Yang S, Sun W, Zhang F et al (2013b) Phylogenetically diverse denitrifying and ammonia-oxidizing bacteria in corals Alcyonium gracillimum and Tubastraea coccinea. Mar Biotechnol 15:540–551

    Article  CAS  PubMed  Google Scholar 

  • Yokouchi H, Fukuoka Y, Mukoyama D et al (2006) Whole-metagenome amplification of a microbial community associated with scleractinian coral by multiple displacement amplification using phi29 polymerase. Environ Microbiol 8:1155–1163

    Article  CAS  PubMed  Google Scholar 

  • Zhang XY, Bao J, Wang GH et al (2012) Diversity and antimicrobial activity of culturable fungi isolated from six species of the South China Sea gorgonians. Microb Ecol 64:617–627

    Article  CAS  PubMed  Google Scholar 

  • Zheng CJ, Shao CL, Guo ZY et al (2012) Bioactive hydroanthraquinones and anthraquinone dimers from a soft coral-derived Alternaria sp. fungus. J Nat Prod 75:189–197

    Article  CAS  PubMed  Google Scholar 

  • Zheng CJ, Shao CL, Wu LY et al (2013) Bioactive phenylalanine derivatives and cytochalasins from the soft coral-derived fungus, Aspergillus elegans. Mar Drugs 11:2054–2068

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhuang Y, Teng X, Wang Y et al (2011) New quinazolinone alkaloids within rare amino acid residue from coral-associated fungus, Aspergillus versicolor LCJ-5-4. Org Lett 13:1130–1133

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

This work was supported by the National Major Scientific Research Program of China (2013CB956103).

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Authors and Affiliations

  1. Marine Biotechnology Laboratory, State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, People’s Republic of China

    Wei Sun, Ramasamy Anbuchezhian & Zhiyong Li

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Correspondence to Zhiyong Li .

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  1. Biological, Geological and Env Scie, University of Bologna, Bologna, Italy

    Stefano Goffredo

  2. Fac. Life Sciences, Bar-Ilan University, Ramat-Gan, Israel

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Sun, W., Anbuchezhian, R., Li, Z. (2016). Association of Coral-Microbes, and the Ecological Roles of Microbial Symbionts in Corals. In: Goffredo, S., Dubinsky, Z. (eds) The Cnidaria, Past, Present and Future. Springer, Cham. https://doi.org/10.1007/978-3-319-31305-4_22

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