Abstract
Alkaptonuria (AKU) is an inherited disorder of metabolism of aromatic amino acids phenylalanine and tyrosine that is caused due to the lack of activity of the enzyme homogentisate 1,2-dioxygenase (HGD). The homogentisic acid is not metabolised; it accumulates in the body and is excreted into urine.
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Rovenský, J., Imrich, R., Urbánek, T., Bošák, V. (2017). Alkaptonuria and Ochronosis. In: Rovenský, J. (eds) Gerontorheumatology. Springer, Cham. https://doi.org/10.1007/978-3-319-31169-2_19
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DOI: https://doi.org/10.1007/978-3-319-31169-2_19
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