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Molecular Biomarkers in Prognostication of Uveal Melanoma

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Molecular Cytopathology

Part of the book series: Essentials in Cytopathology ((EICP,volume 26))

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Abstract

Uveal melanoma arises from melanocytes of the uveal tract (iris, ciliary body, and choroid) and represents the most common intraocular malignancy in adults. The mean age-adjusted incidence of uveal melanoma in the USA is approximately 4.3 new cases per million people, with no clear variation by latitude. Males have a higher incidence than females (4.9 vs. 3.7 per million). Uveal melanoma is diagnosed mostly at older ages, with a progressively rising, age-specific, incidence rate that peaks near the age of 70 years. Diagnosis often occurs late in the course of disease, and prognosis is generally poor.

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Correspondence to Charles V. Biscotti M.D. .

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Biscotti, C.V. (2016). Molecular Biomarkers in Prognostication of Uveal Melanoma. In: Yang, B., Rao, J. (eds) Molecular Cytopathology. Essentials in Cytopathology, vol 26. Springer, Cham. https://doi.org/10.1007/978-3-319-30741-1_14

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  • DOI: https://doi.org/10.1007/978-3-319-30741-1_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-30739-8

  • Online ISBN: 978-3-319-30741-1

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