Abstract
Once the initial carious decay crosses the whole enamel thickness, diffusion occurs at the dentinoenamel junction, mostly in the mantle dentin direction where the dentinal carious decay displays an early development. After the collapse of the non-sustained enamel surface, a cavity starts to be formed, containing residual food debris (zone of degradation), above a zone of bacterial invasion. The demineralized dentin layer displays an infected zone, where dentinal tubules are enlarged. They are filled with active bacteria. Intertubular dentin is demineralized, removable manually by sharp curettes and forming the soft carious dentin. The affected zone is located beneath. Intertubular dentin is gradually recovering from the demineralization process. The lumens of tubules display normal diameter, and the peritubular dentin gradually reappears. In the sclerotic zone, either reprecipitation of non-apatitic mineral contributes to fill partially the lumen of the tubules or apatitic-like structures seal more or less homogeneously the lumen of tubules (intratubular mineralization). The subjacent layer contains lipid-loaded odontoblast processes. These cells contribute to the formation of reactionary dentin. They are implicated in slowing down the speed of diffusion of the carious lesion in the crown.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bjorndal L, Thylstrup A. A structural analysis of approximal enamel caries lesions and subjacent dentin reactions. Eur J Oral Sci. 1995;103:25–31.
Boushell LW, Nagoka H, Nagoka H, Yamauchi M. Increased matrix metalloproteinase-2 and bone SialoProtein response to human coronal caries. Caries Research. 2011;45:453–9.
Ekstrand KR, Ricketts DN, Kidd EA. Do occlusal carious lesions spread laterally at the enamel-dentin junction? A histopathological study. Clin Oral Investig. 1998;2:15–20.
Fusayama T. Two layers of carious dentin. Diagnosis and treatment. Oper Dent. 1979;45:63–70.
Goldberg M, Kulkarni AB, Young M, Boskey A. Dentin: structure, composition and mineralization. The role of dentin ECM in dentin formation and mineralization. Front BioSci (Elite Ed). 2011;3:711–35.
Mazzoni A, Tjäderhane L, Checchi V, Di Lenarda R, Salo T, Tay FR, Pashley DH, Breschi L. Role of dentin MMPs in caries progression and bond stability. J Dent Res. 2015;94(2):241–251.
Newbrun E. Cariology. Baltimore/London: Williams & Wilkins; 1983. p. 245–51.
Takuma S. Electron microscopy of the structure around the dentinal tubule. J Dent Res. 1960;39:973–81.
Yamada T, Nakamura K, Iwaku M, Fusayama T. The extent of odontoblast process in normal and carious human dentin. J Dent Res. 1983;62:798–802.
Zavgorodnuy AV, Rohanizadeh R, Swain MV. Ultrastructure of dentine carious lesions. Arch Oral Biol. 2008;53:124–32.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Goldberg, M. (2016). From the Initial Carious Lesion of Enamel to the Early Development of Coronal Dentin Carious Lesion. In: Goldberg, M. (eds) Understanding Dental Caries. Springer, Cham. https://doi.org/10.1007/978-3-319-30552-3_7
Download citation
DOI: https://doi.org/10.1007/978-3-319-30552-3_7
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-30550-9
Online ISBN: 978-3-319-30552-3
eBook Packages: MedicineMedicine (R0)