Acquired Demyelinating Diseases

  • Àlex Rovira
  • Kelly K. KoellerEmail author


Demyelinating disorders of the central nervous system (CNS) have a variety of etiologies and can be separated into primary (e.g., multiple sclerosis (MS) and other idiopathic inflammatory-demyelinating diseases) and secondary (e.g., infectious, ischemic, metabolic, or toxic) diseases. Brain and spinal cord magnetic resonance imaging (MRI) is the imaging modality of choice to assess demyelinating disorders and, together with the clinical and laboratory findings, can accurately classify them in most cases [1–3]. This review will highlight the important imaging manifestations of some acquired demyelinating diseases that allow more specific diagnosis.


Demyelinating diseases White matter Brain Multiple sclerosis Metabolic diseases Ischemia Radiotherapy Chemotherapy MR imaging NMO ADEM Diagnosis Acquired 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Section of Neuroradiology and MR Unit (IDI), Department of RadiologyHospital Universitari Vall d’Hebron, Autonomous University of BarcelonaBarcelonaSpain
  2. 2.Section of Neuroradiology, Department of RadiologyMayo ClinicRochesterUSA

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